EIF2AK4 Antibody

Datasheet
Code CSB-PA555295
Former Code(s) CSB-PA264112
Size US$299
Uniprot No. Q9P2K8
Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA555295(EIF2AK4 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA555295(EIF2AK4 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
Immunogen Fusion protein of Human EIF2AK4
Raised in Rabbit
Species Reactivity Human,Mouse
Tested Applications ELISA,IHC;ELISA:1:2000-1:5000,IHC:1:50-1:200
Relevance EIF2AK4 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2S1; MIM 603907) to downregulate protein synthesis in response to varied cellular stresses
Form Liquid
Conjugate Non-conjugated
Storage Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method Antigen affinity purification
Isotype IgG
Alias eukaryotic translation initiation factor 2 alpha kinase 4
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Target Names EIF2AK4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Still Have Questions? Leave a Message or Start an on-line Chat
Function Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2-alpha/EIF2S1) on 'Ser-52' in response to low amino acid availability
Involvement in disease Pulmonary venoocclusive disease 2, autosomal recessive (PVOD2)
Subcellular Location Cytoplasm
Protein Families Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily
Tissue Specificity Widely expressed (PubMed:10504407). Expressed in lung, smooth muscle cells and macrophages (PubMed:24292273).
Database Links

HGNC: 19687

OMIM: 234810

KEGG: hsa:440275

STRING: 9606.ENSP00000263791

UniGene: Hs.656673

Pathway Autophagy
Protein processing in endoplasmic reticulum

Related Products

EIF2AK4 Antibodies

EIF2AK4 Antibodies for Human

EIF2AK4 Antibodies for Homo sapiens (Human)

EIF2AK4 Proteins

EIF2AK4 Proteins for Homo sapiens (Human)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.

Wait!

Join the 25,000 subscribers to get research hotpots, technical tips, latest information on events, sales and offers.

Sign up now!

We don't deal in spam.