GNAS Antibody

Datasheet

Code	CSB-PA352389LA01HU
Size	US$166
	Order now
Image	Western Blot Positive WB detected in: Rat brain tissue, Mouse brain tissue All lanes: GNAS antibody at 3µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 46, 45, 112, 110, 78, 29 kDa Observed band size: 46 kDa Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA352389LA01HU at dilution of 1:100 Immunofluorescent analysis of MCF-7 cells using CSB-PA352389LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The Latest Promotion
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) GNAS Polyclonal antibody

Uniprot No.

P63092

Target Names

GNAS

Alternative Names

Adenylate cyclase-stimulating G alpha protein antibody; AHO antibody; alternative gene product encoded by XL-exon antibody; C20orf45 antibody; extra large alphas protein antibody; GNAS antibody; GNAS complex locus antibody; GNAS1 antibody; GNAS1 gene, formerly antibody; GNAS1, formerly antibody; GNAS2_HUMAN antibody; GPSA antibody; GSA antibody; GSP antibody; guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 antibody; guanine nucleotide regulatory protein antibody; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short antibody; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas antibody; NESP antibody; neuroendocrine secretory protein antibody; PHP1A antibody; PHP1B antibody; PHP1C antibody; POH antibody; protein ALEX antibody; secretogranin VI antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Human Guanine nucleotide-binding protein G(s) subunit alpha isoforms short protein (1-394AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The GNAS Antibody (Product code: CSB-PA352389LA01HU) is Non-conjugated. For GNAS Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA352389LB01HU	GNAS Antibody, HRP conjugated	ELISA
FITC	CSB-PA352389LC01HU	GNAS Antibody, FITC conjugated
Biotin	CSB-PA352389LD01HU	GNAS Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

The GNAS antibody is generated by immunizing rabbits with the full-length amino acids of the human GNAS protein. It is a polyclonal antibody and occurs as an unconjugated IgG. Its purity is greater than 95% using protein G purified. It shows cross-reactivity with human, mouse, and rat GNAS protein. This GNAS antibody is available for use in ELISA, WB, IHC, and IF applications. The target protein GNAS is the stimulatory alpha subunit of the guanine nucleotide-binding protein (G protein), which is a widely expressed signaling protein essential for the actions of many hormones and other endogenous molecules.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.

Involvement in disease

Albright hereditary osteodystrophy (AHO); Pseudohypoparathyroidism 1A (PHP1A); McCune-Albright syndrome (MAS); Progressive osseous heteroplasia (POH); ACTH-independent macronodular adrenal hyperplasia 1 (AIMAH1); Pseudohypoparathyroidism 1B (PHP1B); GNAS hyperfunction (GNASHYP); Pseudohypoparathyroidism 1C (PHP1C)

Subcellular Location

Cell membrane; Lipid-anchor.

Protein Families

G-alpha family, G(s) subfamily

Database Links

HGNC: 4392

OMIM: 103580

KEGG: hsa:2778

UniGene: Hs.125898

Promotions

Transmembrane Protein Questionnaire with Gifts

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

IL-6: an Important Participant in the Inflammatory Cascade, One of the Most Functional Cytokines in Various Diseases Research! Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Calcium signaling pathway cAMP signaling pathway Estrogen signaling pathway Melanogenesis Gap junction Vascular smooth muscle contraction Th17 cell differentiation Thyroid hormone synthesis Glucagon signaling pathway Oxidative Phosphorylation Phospholipase D signaling pathway Rap1 signaling pathway Glutamatergic synapse

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address