IL4 Antibody

Datasheet
Code CSB-PA556277
Product Type Polyclonal Antibody
Size US$297
Uniprot No. P05112
Image
  • Western blot analysis of extracts from HeLa cells, using IL4 antibody.
Immunogen Synthesized peptide derived from C-terminal of Human IL4.
Raised in Rabbit
Species Reactivity Human
Specificity The antibody detects endogenous levels of total IL4 protein.
Tested Applications ELISA,WB;WB:1:500-1:3000
Relevance Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.

Yokota T., Proc. Natl. Acad. Sci. U.S.A. 83:5894-5898(1986).
Arai N., J. Immunol. 142:274-282(1989).
Klein S.C., Immunogenetics 41:57-57(1995).
Form Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality Polyclonal
Alias B cell growth factor 1; B cell stimulatory factor 1; B-cell stimulatory factor 1; BCGF-1; BCGF1
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Target Names IL4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Participates in at least several B-cell activation processes as well as of other cell types
Involvement in disease Ischemic stroke (ISCHSTR)
Subcellular Location Secreted
Protein Families IL-4/IL-13 family
Database Links

HGNC: 6014

OMIM: 147780

KEGG: hsa:3565

STRING: 9606.ENSP00000231449

UniGene: Hs.73917

Pathway Jak-STAT signaling pathway
PI3K-Akt signaling pathway
Fc epsilon RI signaling pathway
Hematopoietic cell lineage
IL-17 signaling pathway
T cell receptor signaling pathway
Th1 and Th2 cell differentiation
Th17 cell differentiation

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