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| Code | CSB-PA015270GA01HU |
| Product Type | Purified Rabbit Anti human PolyClonal Antibody |
| Size | US$685 |
| Uniprot No. | P01106 |
| Immunogen | Human MYC |
| Species Reactivity | Human,Mouse,Rat |
| Tested Applications | ELISA,WB, IP, IHC, IF, FC |
| Storage Buffer | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles. |
| Purification Method | Antigen Affinity Purified |
| Isotype | IgG |
| Alias | 48.8kd; |
| Immunogen Species | Homo sapiens (Human) |
| Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunoprecipitation (IP) Protocol Immunohistochemistry (IHC) Protocol Immunofluorescence (IF) Protocol Flow Cytometry (FC) Protocol |
| Target Names | MYC |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Target Details | This protein is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt s lymphomas, suggesting its importance in the normal function of this gene. |
| HGNC | 1052 |
| RGD | 621786 |
| MGI | 108092 |
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| Function | Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis |
| Involvement in disease | Burkitt lymphoma (BL) |
| Subcellular Location | Nucleus, nucleoplasm, Nucleus, nucleolus |
| Database Links |
HGNC: 7553 OMIM: 113970 KEGG: hsa:4609 STRING: 9606.ENSP00000367207 UniGene: Hs.202453 |
| Pathway |
ErbB signaling pathway
Hippo signaling pathway Jak-STAT signaling pathway MAPK signaling pathway PI3K-Akt signaling pathway TGF-beta signaling pathway Wnt signaling pathway Cell cycle Cellular senescence Signaling pathways regulating pluripotency of stem cells |
MYC Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-RA015270A62phHU | Phospho-MYC (S62) Antibody | Human | ELISA, WB, IF |
| CSB-RA015270A58-62phHU | Phospho-MYC (T58+S62) Antibody | Human | ELISA, WB |
| CSB-PA598712 | MYC (Ab-58) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA930453 | MYC (Ab-358) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA945395 | Phospho-MYC (Thr58) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA239396 | Phospho-MYC (Thr358) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA038920 | Phospho-MYC (Ser373) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA062361 | Phospho-MYC (Ser62) Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA552586 | MYC (Ab-373) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA153029 | MYC Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA000389 | MYC Antibody | Human | WB |
| CSB-PA000503 | Phospho-MYC (T58) Antibody | Human,Mouse,Rat | WB,IHC,IP,ELISA |
| CSB-PA000729 | Phospho-MYC (S62) Antibody | Human,Mouse,Rat | WB,IHC,IF,ELISA |
| CSB-PA001729 | MYC Antibody | Human,Mouse,Rat | WB,IHC,ELISA |
| CSB-PA010301 | Phospho-MYC (S373) Antibody | Human,Mouse,Rat | IHC,IP,ELISA |
| CSB-PA010303 | Phospho-MYC (T358) Antibody | Human,Mouse,Rat | IHC,IP,ELISA |
| CSB-PA407491 | MYC Antibody | Human,Rat | ELISA,WB,IHC |
MYC Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA02589A0Rb | MYC Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA02589B0Rb | MYC Antibody, HRP conjugated | Human | ELISA |
| CSB-PA02589C0Rb | MYC Antibody, FITC conjugated | Human | ELISA |
| CSB-PA02589D0Rb | MYC Antibody, Biotin conjugated | Human | ELISA |
MYC Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP015270HU CSB-BP015270HU CSB-MP015270HU |
Recombinant Human Myc proto-oncogene protein(MYC) | Yeast Baculovirus Mammalian cell |
| CSB-EP015270HU | Recombinant Human Myc proto-oncogene protein(MYC),Escherichia Coli | E.coli |
| CSB-RP025844h | Recombinant Human Myc proto-oncogene protein(MYC) | E.coli |
| CSB-EP015270HU1 | Recombinant Human Myc proto-oncogene protein(MYC),partial | E.coli |
MYC ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E09260h | Human c-myc Oncogene product,c-myc ELISA Kit | serum, plasma, tissue homogenates, cell lysates | 0.078 ng/mL |
2-hydroxyisobutyryl-HIST1H2BC (K34) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human, Rat
2-hydroxyisobutyryl-HIST1H3A (K18) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human, Rat
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