MYC Antibody

Datasheet
Code CSB-PA001729
Former Code(s) CSB-PA001730,CSB-PA001731,CSB-PA010304,CSB-PA010306
Size US$167
Uniprot No. P01106
Image
  • Western Blot analysis of HuvEc cells using c-Myc Polyclonal Antibody
  • Western Blot analysis of various cells using c-Myc Polyclonal Antibody
Protocols Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol
Immunogen Synthesized peptide derived from Human c-Myc around the non-phosphorylation site of T358.
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications WB,IHC,ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000
Form Liquid
Conjugate Non-conjugated
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Alias MYC; BHLHE39; Myc proto-oncogene protein; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64
Immunogen Species Homo sapiens (Human)
Target Names MYC
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis
Involvement in disease Burkitt lymphoma (BL)
Subcellular Location Nucleus, nucleoplasm, Nucleus, nucleolus
Database Links

HGNC: 7553

OMIM: 113970

KEGG: hsa:4609

STRING: 9606.ENSP00000367207

UniGene: Hs.202453

Pathway ErbB signaling pathway
Hippo signaling pathway
Jak-STAT signaling pathway
MAPK signaling pathway
PI3K-Akt signaling pathway
TGF-beta signaling pathway
Wnt signaling pathway
Cell cycle
Cellular senescence
Signaling pathways regulating pluripotency of stem cells

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