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Code | CSB-PA822274LA01HU |
Size | US$299 |
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Full Product Name | Rabbit anti-Homo sapiens (Human) NECTIN4 Polyclonal antibody | ||||
Uniprot No. | Q96NY8 | ||||
Target Names | NECTIN4 | ||||
Alternative Names |
DKFZp686K05193 antibody; EDSS1 antibody; Ig superfamily receptor LNIR antibody; Nectin 4 antibody; Nectin-4 antibody; poliovirus receptor-related 4 antibody; Processed poliovirus receptor-related protein 4 antibody; PRR4 antibody; pvrl4 antibody; PVRL4_HUMAN antibody
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Raised in | Rabbit | ||||
Species Reactivity | Human | ||||
Immunogen | Recombinant Human Nectin-4 protein (91-199AA) | ||||
Immunogen Species | Homo sapiens (Human) | ||||
Conjugate | Non-conjugated The NECTIN4 Antibody (Product code: CSB-PA822274LA01HU) is Non-conjugated. For NECTIN4 Antibody with conjugates, please check the following table. |
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Clonality | Polyclonal | ||||
Isotype | IgG | ||||
Purification Method | >95%, Protein G purified | ||||
Concentration | It differs from different batches. Please contact us to confirm it. | ||||
Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
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Form | Liquid | ||||
Tested Applications | ELISA, IF | ||||
Recommended Dilution |
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Protocols | ELISA Protocol Immunofluorescence (IF) Protocol |
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Troubleshooting and FAQs | Antibody FAQs | ||||
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||
Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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Function |
Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.; (Microbial infection) Acts as a receptor for measles virus.
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Gene References into Functions |
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Involvement in disease | Ectodermal dysplasia-syndactyly syndrome 1 (EDSS1) |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Cell junction, adherens junction. Note=Colocalizes with AFDN at cadherin-based adherens junctions (PubMed:11544254).; [Processed poliovirus receptor-related protein 4]: Secreted. Note=The secreted form is found in breast tumor patients (PubMed:15784625). |
Protein Families | Nectin family |
Tissue Specificity | Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma. |
Database Links |
HGNC: 19688 OMIM: 609607 KEGG: hsa:81607 STRING: 9606.ENSP00000356991 UniGene: Hs.492490 |