Code | CSB-PA071831 |
Size | US$299 |
Uniprot No. | Q13131 |
Image |
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Immunogen | Synthetic peptide of Human PRKAA1 |
Raised in | Rabbit |
Species Reactivity | Human,Mouse,Rat |
Tested Applications | ELISA,WB,IHC;ELISA:1:2000-1:10000,WB:1:200-1:1000,IHC:1:100-1:300 |
Relevance | The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Form | Liquid |
Conjugate | Non-conjugated |
Storage Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method | Antigen affinity purification |
Isotype | IgG |
Alias | protein kinase, AMP-activated, alpha 1 catalytic subunit |
Immunogen Species | Homo sapiens (Human) |
Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol |
Target Names | PRKAA1 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Still Have Questions? | Leave a Message or Start an on-line Chat |
Function | Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes |
Subcellular Location | Cytoplasm, Nucleus |
Protein Families | Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily |
Database Links |
HGNC: 9376 OMIM: 602739 KEGG: hsa:5562 STRING: 9606.ENSP00000346148 UniGene: Hs.43322 |
Pathway |
mTOR signaling pathway
PI3K-Akt signaling pathway Autophagy Adipocytokine signaling pathway AMPK signaling Apelin signaling pathway FoxO signaling pathway Glucagon signaling pathway Insulin signaling pathway |
PRKAA1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA618759KA01HU | PRKAA1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IP |
CSB-PA261465 | Phospho-PRKAA1/PRKAA2 (Ser487) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA592613 | PRKAA1/PRKAA2 (Ab-487) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA913725 | PRKAA1 (Ab-174/172) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA131259 | PRKAA1 Antibody | Human,Mouse,Rat | WB,IHC,IF,ELISA |
CSB-PA953053 | Phospho-PRKAA1 (S496) Antibody | Human,Mouse,Rat | WB,IHC,ELISA |
CSB-PA865713 | PRKAA1 Antibody | Human,Mouse,Rat | WB |
CSB-PA801858 | PRKAA1 Antibody | Human,Mouse,Rat | WB,IHC |
CSB-PA228254 | PRKAA1 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA345903 | PRKAA1 Antibody | Human,Mouse,Rat | ELISA,IHC |
PRKAA1 Antibodies for Human
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA618759LA01HU | PRKAA1 Antibody | Human, Mouse | ELISA, WB, IHC, IF |
CSB-PA618759LB01HU | PRKAA1 Antibody, HRP conjugated | Human | ELISA |
CSB-PA618759LC01HU | PRKAA1 Antibody, FITC conjugated | Human | ELISA |
CSB-PA618759LD01HU | PRKAA1 Antibody, Biotin conjugated | Human | ELISA |
PRKAA1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP618759HU CSB-EP618759HU CSB-BP618759HU CSB-MP618759HU |
Recombinant Human 5'-AMP-activated protein kinase catalytic subunit alpha-1(PRKAA1) | Yeast E.coli Baculovirus Mammalian cell |
2-hydroxyisobutyryl-HIST1H1C (K158) Antibody
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Species Reactivity: Human
2-hydroxyisobutyryl-HIST1H2AG (K74) Antibody
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Species Reactivity: Human, Rat
2-hydroxyisobutyryl-HIST1H2BC (K120) Antibody
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Species Reactivity: Human, Rat
2-hydroxyisobutyryl-HIST1H2BC (K20) Antibody
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Species Reactivity: Human, Rat
2-hydroxyisobutyryl-HIST1H2BC (K24) Antibody
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Species Reactivity: Human, Mouse, Rat
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Species Reactivity: Human, Mouse, Rat
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