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| Code | CSB-PA050275 |
| Size | US$167 |
| Uniprot No. | P19438 |
| Protocols | Immunohistochemistry (IHC) Protocol ELISA Protocol |
| Immunogen | Synthesized peptide derived from the C-terminal region of Human TNF-R1. |
| Raised in | Rabbit |
| Species Reactivity | Human,Mouse,Rat |
| Tested Applications | IHC,ELISA;IHC:1/100-1/300.ELISA:1/20000 |
| Form | Liquid |
| Conjugate | Non-conjugated |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Isotype | IgG |
| Alias | TNFRSF1A; TNFAR; TNFR1; Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60; CD antigen CD120a |
| Immunogen Species | Homo sapiens (Human) |
| Target Names | TNFRSF1A |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
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| Function | Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. |
| Involvement in disease | Familial hibernian fever (FHF); Multiple sclerosis 5 (MS5) |
| Subcellular Location | Cell membrane, Single-pass type I membrane protein, Golgi apparatus membrane, Single-pass type I membrane protein, Secreted, Note=A secreted form is produced through proteolytic processing, SUBCELLULAR LOCATION: Isoform 4: Secreted |
| Database Links |
HGNC: 11916 OMIM: 142680 KEGG: hsa:7132 STRING: 9606.ENSP00000162749 UniGene: Hs.279594 |
| Pathway |
MAPK signaling pathway
mTOR signaling pathway NF-kappa B signaling pathway TNF signaling pathway Apoptosis Necroptosis Osteoclast differentiation Adipocytokine signaling pathway |
TNFRSF1A Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA023977LD01HU | TNFRSF1A Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA023977LA01HU | TNFRSF1A Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA023977LB01HU | TNFRSF1A Antibody, HRP conjugated | Human | ELISA |
| CSB-PA023977LC01HU | TNFRSF1A Antibody, FITC conjugated | Human | ELISA |
| CSB-PA023977GA01HU | TNFRSF1A Antibody | Human | ELISA,WB |
| CSB-PA973584 | TNFRSF1A Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA023977XA01HU | TNR1A Antibody | Homo sapiens (Human) | ELISA, WB (ensure identification of antigen) |
TNFRSF1A Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-AP004971HU | Recombinant Human Tumor necrosis factor receptor superfamily member 1A(TNFRSF1A),partial (Active) | E.coli |
| CSB-EP023977HU1 CSB-BP023977HU1 CSB-MP023977HU1 |
Recombinant Human Tumor necrosis factor receptor superfamily member 1A(TNFRSF1A),partial | E.coli Baculovirus Mammalian cell |
| CSB-AP002361HU | Recombinant Human Tumor necrosis factor receptor superfamily member 1A protein(TNFRSF1A) (Active) | E.coli |
| CSB-CF023977HU | Recombinant Human Tumor necrosis factor receptor superfamily member 1A(TNFRSF1A) | in vitro E.coli expression system |
| CSB-YP023977HU1 | Recombinant Human Tumor necrosis factor receptor superfamily member 1A(TNFRSF1A),partial | Yeast |
| CSB-RP072244h | Recombinant Human Tumor necrosis factor receptor superfamily member 1A(TNFRSF1A),partial | E.coli |
TNFRSF1A ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E04736h | Human Tumor necrosis factor soluble receptor Ⅰ,TNFsR-ⅠELISA KIT | serum, plasma, tissue homogenates, urine | 65 pg/mL |
2-hydroxyisobutyryl-HIST1H2BC (K12) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human
2-hydroxyisobutyryl-HIST1H4A (K5) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human
