The following TNFRSF1A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TNFRSF1A Antibodies

TNFRSF1A Antibodies for Homo sapiens (Human)

TNFRSF1A Proteins

TNFRSF1A Proteins for Homo sapiens (Human)

TNFRSF1A Proteins for Rattus norvegicus (Rat)

TNFRSF1A Proteins for Mus musculus (Mouse)

TNFRSF1A Proteins for Sus scrofa (Pig)

TNFRSF1A Proteins for Bos taurus (Bovine)


TNFRSF1A ELISA Kit for Homo sapiens (Human)

TNFRSF1A ELISA Kit for Mus musculus (Mouse)

TNFRSF1A ELISA Kit for Rattus norvegicus (Rat)

TNFRSF1A Background

Tumor necrosis factor receptor superfamily member 1A is a protein in humans that is encoded by TNFRSF1A gene. TNFRSF1A is a receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

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