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| Product Type | Recombinant Protein |
| Uniprot No. | Q8MKH0 |
| Abbreviation | IL6 |
| Species | Saimiri sciureus (Common squirrel monkey) |
| Gene Names | IL6 |
| Protein Names | Recommended name: Interleukin-6 Short name= IL-6 |
| Storage | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
| Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
| Function | Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation (By similarity). |
| Subcellular Location | Secreted |
| Protein Families | IL-6 superfamily |
| Pathway |
HIF-1 signaling pathway
Jak-STAT signaling pathway PI3K-Akt signaling pathway TNF signaling pathway Cellular senescence Hematopoietic cell lineage IL-17 signaling pathway NOD-like receptor signaling pathway Th17 cell differentiation Toll-like receptor signaling pathway AGE-RAGE signaling pathway in diabetic complications FoxO signaling pathway Inflammatory Pain |
| Product Name | Recombinant Saimiri sciureus Interleukin-6(IL6),Yeast |
| Code | CSB-YP847583SWD |
| Size | Pls inquiry other sizes |
| Source | Yeast |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Sequence | V TLGEDSKEVA APNRQLLTST ERIDKHIWYI LDGISALRKE ICNKSNMCES SKEALAENNL NLPKMAEKDG CFQSGFNEET CLLKITTGLL EFEVYLEYLQ NRFESSKEQA GAVQMSTKGL IQSLQRKAKN LSAIATPDPA TNASLLTKLQ AQDQWLQGVT THLILRSFKE FLQCSLRALR QM |
| Expression Region | 30-212 |
| Protein Description | Full Length of Mature Protein |
| Storage Buffer | Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0 |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Product Name | Recombinant Saimiri sciureus Interleukin-6(IL6),E.coli |
| Code | CSB-EP847583SWD |
| Size | Pls inquiry other sizes |
| Source | E.coli |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged and C-terminal Myc-tagged N-terminal His-SUMO-tagged and C-terminal Myc-tagged N-terminal His-B2M-tagged and C-terminal Myc-tagged N-terminal His-GST-tagged and C-terminal Myc-tagged N-terminal His-tagged N-terminal His-SUMO-tagged N-terminal His-B2M-tagged N-terminal His-GST-tagged N-terminal GST-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Sequence | V TLGEDSKEVA APNRQLLTST ERIDKHIWYI LDGISALRKE ICNKSNMCES SKEALAENNL NLPKMAEKDG CFQSGFNEET CLLKITTGLL EFEVYLEYLQ NRFESSKEQA GAVQMSTKGL IQSLQRKAKN LSAIATPDPA TNASLLTKLQ AQDQWLQGVT THLILRSFKE FLQCSLRALR QM |
| Expression Region | 30-212 |
| Protein Description | Full Length of Mature Protein |
| Storage Buffer | Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0 |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Product Name | Recombinant Saimiri sciureus Interleukin-6(IL6),Baculovirus |
| Code | CSB-BP847583SWD |
| Size | Pls inquiry other sizes |
| Source | Baculovirus |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged and C-terminal Myc-tagged N-terminal His-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Sequence | V TLGEDSKEVA APNRQLLTST ERIDKHIWYI LDGISALRKE ICNKSNMCES SKEALAENNL NLPKMAEKDG CFQSGFNEET CLLKITTGLL EFEVYLEYLQ NRFESSKEQA GAVQMSTKGL IQSLQRKAKN LSAIATPDPA TNASLLTKLQ AQDQWLQGVT THLILRSFKE FLQCSLRALR QM |
| Expression Region | 30-212 |
| Protein Description | Full Length of Mature Protein |
| Storage Buffer | Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0 |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Product Name | Recombinant Saimiri sciureus Interleukin-6(IL6),Mammalian cell |
| Code | CSB-MP847583SWD |
| Size | Pls inquiry other sizes |
| Source | Mammalian cell |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged and C-terminal Myc-tagged N-terminal His-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Sequence | V TLGEDSKEVA APNRQLLTST ERIDKHIWYI LDGISALRKE ICNKSNMCES SKEALAENNL NLPKMAEKDG CFQSGFNEET CLLKITTGLL EFEVYLEYLQ NRFESSKEQA GAVQMSTKGL IQSLQRKAKN LSAIATPDPA TNASLLTKLQ AQDQWLQGVT THLILRSFKE FLQCSLRALR QM |
| Expression Region | 30-212 |
| Protein Description | Full Length of Mature Protein |
| Storage Buffer | Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0 |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
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