Code | CSB-RA958910A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:5000 |
FC | 1:20-1:200 |
NR3C1, encoding glucocorticoid receptor (GR), functions as a transcription activator by binding to glucocorticoid to regulate the transcription rates of glucocorticoid-responsive genes in a positive or negative manner. NR3C1 is involved in the regulation of transcription modulation, cell growth, glucocorticoid-induced apoptosis, inflammation, and differentiation. As a homeostatic modulator, NR3C1 plays a critical role in neuroendocrine integration, circadian rhythm, immune system control, and glucose metabolism. NR3C1 is also related to tumorigenesis, and reduction or absence of NR3C1 expression has been observed in colorectal cancer.
The recombinant NR3C1 antibody was produced by cloning antibody genes into an expression vectors, which were subsequently introduced into mammalian cells to provide animal-free antibody production. This NR3C1 antibody has been validated in ELISA, WB, FC. It has the features of improved affinity, stability, and consistency between different batches.There are currently no reviews for this product.