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| Code | CSB-RA446786A0HU |
| Size | US$210 |
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| Application | Recommended Dilution |
|---|---|
| WB | 1:500-1:2000 |
The ULBP1 recombinant monoclonal antibody was generated using the synthesized peptide derived from human ULBP1 protein as the immunogen. To obtain the DNA sequence of the SLC39A6 monoclonal antibody, the cDNA was sequenced and the gene was cloned into a plasmid vector. The plasmid vector containing the ULBP1 monoclonal antibody gene was then transfected into a host cell using an appropriate transfection method. The resulting ULBP1 recombinant monoclonal antibody underwent affinity-chromatography purification and was tested for specificity in an ELISA and WB applications. It can react with human ULBP1 protein.
ULBP1 is a glycoprotein that functions as a ligand for the NKG2D receptor, a type of immune cell receptor that is primarily expressed on the surface of natural killer (NK) cells and a subset of T cells. ULBP1 is expressed on the surface of stressed or infected cells and plays an important role in the immune system's ability to recognize and eliminate infected or abnormal cells. When binding to NKG2D on the surface of NK cells, ULBP1 triggers a series of events that ultimately result in the activation of the NK cell and the destruction of the target cell.
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