These Surface Markers Help You Identify Lymphocytes
These Surface Markers Help You Identify LymphocytesLymphocytes are the smallest white blood cells. It is an immune-recognition cell line produced by lymphoid organs. According to their migration, surface molecules and functions, they can be divided into three categories:...
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Cell Differentiation Determines the Fate of Cells
Cell Differentiation Determines the Fate of CellsCell differentiation is the process where a cell changes from one type to many different types. In the process of cell differentiation, there are differences in morphological structure and physiological function. All org...
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CAR-T Cell Therapy- An Useful Treatment To Cancer
CAR-T Cell Therapy- An Useful Treatment To CancerGenerally speaking, the foundations of cancer treatment were surgery, chemotherapy, and radiation therapy. But over the past several years, immunotherapy, one type of therapies enlists and strengthens the power of a pati...
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LPS/TLR4 Signal Transduction Pathway
LPS/TLR4 Signal Transduction PathwayIn 1980, Nüsslein-Volhard et al. discovered a gene that determines the dorsal-ventral differentiation in the development of Drosophila embryos and named it Toll [1] [2]. Later, similar homologous receptors were found in...
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What Are the Effects of Abnormalities in the ALK Gene
What Are the Effects of Abnormalities in the ALK GeneAnaplastic lymphoma kinase (ALK) is a transmembrane receptor tyrosine kinase of the insulin receptor superfamily. It is highly homologous with leukocyte tyrosine kinase [1]. ALK plays a major role in the develop...
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These Tumor Databases You Have To Know
These Tumor Databases You Have To KnowCurrently, malignant tumor has become one of the causes of death. The incidence of cancer is increasing globally and the age of onset is getting younger. In 2019, the latest data published by A Cancer Journ...
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Toll-like Receptors--The Eye of Innate Immunity
Toll-like Receptors--The Eye of Innate ImmunityToll-like receptors (TLRs) is a type I transmembrane protein, can identify different pathogen associated molecular patterns (PAMPs), belongs to the surface of the pattern recognition receptors (PRRs). Toll-like receptors...
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Chemokine Receptors – One Kind of Powerful Seven Transmembrane Spanning G Protein-coupled Receptor
Chemokine Receptors – One Kind of Powerful Seven Transmembrane Spanning G Protein-coupled ReceptorChemokine receptors are cytokine receptors expressed on the cell surface as 7-transmembrane proteins that interact with a type of cytokine called a chemokine. Recently, the chemokine receptors have come to attract more a...
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SWISS-PROT: When and How to Use It
SWISS-PROT: When and How to Use ItUniversal Protein Resource (UniProt) comprises the Swiss institute of bioinformatics (SIB), the European institute of bioinformatics (EBI) and the protein information resource (PIR). Its main objective is to provide the ...
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The True Face of Tumor Suppressor Gene p53
The True Face of Tumor Suppressor Gene p53p53 is a tumor suppressor gene that is involved in the development of most cancers in humans. The p53 protein is extremely important for inhibiting the development of cancer. Studies have shown that in addition to tumor ...
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