The Overview of Colony Stimulating Factors
The Overview of Colony Stimulating FactorsColony stimulating factors (CSFs) are glycoproteins that bind to receptor proteins on the surfaces of hemopoietic stem cells, activating intracellular signaling pathways, then promoting production of white blood cells (m...
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The Overview of Chemokine
The Overview of ChemokineChemokines are a series of cytokines with small molecular weight whose main role is the recruitment of leukocyte subsets under homeostatic and pathological conditions. Their name is derived from their ability to induce d...
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General Information of Different Tags
General Information of Different Tags1. Increase Yield of Recombinant Proteins Difficult-to-express proteins can be successfully expressed. For example, one protein can not be expressed with no-tag vector, but can be successfully expressed wi...
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CUSABIO's Five Expression Systems
CUSABIO's Five Expression Systems1. What are CUSABIO's Five Expression Systems? Over more than 11 years, CUSABIO Protein Expression Platform has established five recombinant expression systems, which includes Escherichia coli (E.coli) expressio...
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Tumor Necrosis Factor (TNF)
Tumor Necrosis Factor (TNF)Fig.1 The structure of TNF Tumor necrosis factor was reported firstly by Lloyd J. Old as one kind of cytotoxic factor produced by macrophages, from Memorial Sloan-Kettering Cancer Center, New York, in 19...
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The Application of Nanodiscs in Membrane Proteins
The Application of Nanodiscs in Membrane ProteinsIn the previous chapter, we briefly introduced the basic properties of detergents and their use in membrane proteins. In detergent-containing buffers, most membrane proteins can maintain stability and activity. However...
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Aesthetic Appreciation of Apoptosis Signal Pathway
Aesthetic Appreciation of Apoptosis Signal PathwayApoptosis is mediated primarily through promoting or inhibiting the activation of caspases. Caspases are effectors of cell suicide and cleave multiple substrates, leading to biochemical and morphological changes includin...
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Apoptosisi mediated by death receptor
Apoptosisi mediated by death receptor1. Apoptosis instruction 2. Pathways 2.1 Endogenous mitochondrial pathway 2.2 Endogenous endoplasmic reticulum pathway 2.3 Exogenous death receptor pathway Death receptor (DR...
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Apoptosis mediated by endoplasmic reticulum
Apoptosis mediated by endoplasmic reticulum1. Apoptosis instruction 2. Pathways 2.1 Endogenous mitochondrial pathway 2.2 Endogenous endoplasmic reticulum pathway Endoplasmic reticulum(ER) is the main site of protein processing, as w...
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Apoptosis mediated by mitochondria
Apoptosis mediated by mitochondria 1. Apoptosis instruction Apoptosis is a genetically determined process of cell self-destruction to maintain its own internal environment under physiological or pathological conditions, while it is accompanied...
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