NRG1: an Intriguing Therapeutic Target in DiseasesOn January 7, 2021, the US FDA has granted a fast track designation to Zenocutuzumab (MCLA-128) as a potential therapeutic option for patients with metastatic solid tumors harboring NRG1 gene fusions. Early, Journal of T... Detailed information
STAT3: a Key Transcriptional Regulator in CancerSignal transducer and activator of transcription 3 (STAT3) is a latent cytoplasmic transcription factor [1]. It is interesting that STAT3 was discovered because of its role in the acute-phase response, which is the only ... Detailed information
Melanoma, the Most Serious Type of Skin CancerSkin cancer is the most common of all human cancers. In 2020, more than 100,000 people in the U.S. are expected to be diagnosed with some type of the disease. Nearly 7,000 are expected to die. There are three major types... Detailed information
Leukemia, Why is it So Common?Upon mentioned leukemia, marrow transplantation and anemia as keywords of leukemia come to your mind. Leukemia is the most common cancer in children and teens, accounting for almost 1 out of 3 cancers. Usually, the numbe... Detailed information