Don't Let Hepatocellular Carcinoma "Favor" YouHepatocellular carcinoma (HCC) refers to cancer that originates in the liver, which is distinguished from "secondary" liver cancer that spreads from other organs to the liver. Hepatocellular carcinoma, which accounts for... Detailed information
A Switch that Controls the Entry and Exit of IonsIon channels are pore-forming proteins. It is a passive transport pathway for various inorganic ions across the membrane and an important way for living cells to carry out metabolic activities and material exchange. Ion ... Detailed information
G protein-Coupled Receptor - Targets for Drug TherapyG protein-coupled receptor (GPCR) is a general term for a large class of membrane protein receptors, which also known as seven α-helices transmembrane segment receptors (7TM receptors). It binds to extracellular molecul... Detailed information
A transport machine -- ATP-binding cassetteFigure 1 The Structure of ATP-binding cassette
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ATP-binding cassette (ABC) transporters are the largest known transmembrane protein superfamily, widely distributed in eukar... Detailed information
The Rare Disease-Huntington's DiseaseHuntington's disease (HD) is also known as "hereditary chorea" and "chronic progressive chorea" [1]. Huntington's disease is a hereditary neurodegenerative disease caused by an autosomal dominant mutation that causes the... Detailed information
What Is Immune Checkpoint Therapy?Immune checkpoint therapy, mainly including anti‑CTLA‑4 therapy and anti‑PD‑1/PD‑L1 therapy, which targets regulatory pathways in T cells to enhance antitumor immune responses by blocking the inhibitory signals... Detailed information