CFLAR

CASP8 and FADD-like apoptosis regulator is a protein in humans that is encoded by CFLAR gene. Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.

CFLAR Antibodies

CFLAR Antibodies for Homo sapiens (Human)

CFLAR Antibodies for Human

CFLAR Proteins

CFLAR Proteins for Mus musculus (Mouse)

CFLAR Proteins for Homo sapiens (Human)

CFLAR Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

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