Cbp/p300-interacting transactivator 2 is a protein in humans that is encoded by CITED2 gene. Transcriptional coactivator of the p300/CBP-mediated transcription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor; interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY.

CITED2 Antibodies

CITED2 Antibodies for Homo sapiens (Human)

CITED2 Proteins

CITED2 Proteins for Mus musculus (Mouse)

CITED2 Proteins for Saguinus labiatus (Red-chested mustached tamarin)

CITED2 Proteins for Bos taurus (Bovine)

CITED2 Proteins for Xenopus laevis (African clawed frog)

CITED2 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

CITED2 Proteins for Homo sapiens (Human)


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