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Cbp/p300-interacting transactivator 2 is a protein in humans that is encoded by CITED2 gene. Transcriptional coactivator of the p300/CBP-mediated transcription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor; interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY.
The following CITED2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CITED2 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA005448GA01HU | CITED2 Antibody |
Human,Mouse,Rat | ELISA,WB |
CITED2 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP005448MO CSB-EP005448MO CSB-BP005448MO CSB-MP005448MO CSB-EP005448MO-B |
Recombinant Mouse Cbp/p300-interacting transactivator 2 (Cited2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CITED2 Proteins for Saguinus labiatus (Red-chested mustached tamarin)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP005448SVY CSB-EP005448SVY CSB-BP005448SVY CSB-MP005448SVY CSB-EP005448SVY-B |
Recombinant Saguinus labiatus Cbp/p300-interacting transactivator 2 (CITED2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CITED2 Proteins for Bos taurus (Bovine)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP610826BO CSB-EP610826BO CSB-BP610826BO CSB-MP610826BO CSB-EP610826BO-B |
Recombinant Bovine Cbp/p300-interacting transactivator 2 (CITED2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CITED2 Proteins for Xenopus laevis (African clawed frog)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP726358XBE CSB-EP726358XBE CSB-BP726358XBE CSB-MP726358XBE CSB-EP726358XBE-B |
Recombinant Xenopus laevis Cbp/p300-interacting transactivator 2 (cited2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CITED2 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP764682XBF CSB-EP764682XBF CSB-BP764682XBF CSB-MP764682XBF CSB-EP764682XBF-B |
Recombinant Xenopus tropicalis Cbp/p300-interacting transactivator 2 (cited2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CITED2 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP859529HU CSB-EP859529HU CSB-BP859529HU CSB-MP859529HU CSB-EP859529HU-B |
Recombinant Human Cbp/p300-interacting transactivator 2 (CITED2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
