CNR1

CNR1 (Cannabinoid Receptor 1), also known as CB1 receptor, is a seven-transmembrane protein receptor coupled to G proteins. Its structure comprises an extracellular N-terminal domain, transmembrane region, and intracellular C-terminal domain. It belongs to the cannabinoid receptor family. CB1 receptors are primarily distributed in the central nervous system (the brain and spinal cord) and are one of the primary targets for cannabinoid molecules. CNR1 plays a crucial role in the central nervous system, participating in various physiological processes, including pain perception, emotional regulation, memory, and cognitive function. CNR1 also has a certain role in the immune system. Activation of CB1 receptors can inhibit the activation of immune cells and inflammatory responses. Therefore, CB1 receptor agonists are sometimes researched for the treatment of inflammatory diseases, holding significant importance in biological and medical research.