Transcriptional activator GLI3 is a protein in humans that is encoded by GLI3 gene. Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity.
The following Gli3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
Gli3 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA008881 | GLI3 Antibody |
Human,Mouse,Rat | IHC, IF, ELISA |
Gli3 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP009501HU CSB-EP009501HU CSB-BP009501HU CSB-MP009501HU CSB-EP009501HU-B |
Recombinant Human Transcriptional activator GLI3 (GLI3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Gli3 Proteins for Pan troglodytes (Chimpanzee)
Code | Product Name | Source |
---|---|---|
CSB-YP708418EQV CSB-EP708418EQV CSB-BP708418EQV CSB-MP708418EQV CSB-EP708418EQV-B |
Recombinant Pan troglodytes Transcriptional activator GLI3 (GLI3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Gli3 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP730746MO CSB-EP730746MO CSB-BP730746MO CSB-MP730746MO CSB-EP730746MO-B |
Recombinant Mouse Transcriptional activator GLI3 (Gli3) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Gli3 Proteins for Xenopus laevis (African clawed frog)
Code | Product Name | Source |
---|---|---|
CSB-YP845929XBE CSB-EP845929XBE CSB-BP845929XBE CSB-MP845929XBE CSB-EP845929XBE-B |
Recombinant Xenopus laevis Zinc finger protein GLI3 (gli3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Gli3 Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-YP864270CH CSB-EP864270CH CSB-BP864270CH CSB-MP864270CH CSB-EP864270CH-B |
Recombinant Chicken Transcriptional activator GLI3 (GLI3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |