Insulin receptor substrate 2 is a protein in humans that is encoded by IRS2 gene. May mediate the control of various cellular processes by insulin.
The following IRs2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
IRs2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA969280 | IRS2 Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA036177 | IRS2 Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA169603 | IRS2 Antibody |
Human | WB,ELISA |
CSB-PA011830LA01HU | IRS2 Antibody |
Human | ELISA, IHC, IF |
CSB-PA011830LB01HU | IRS2 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA011830LC01HU | IRS2 Antibody, FITC conjugated |
Human | |
CSB-PA011830LD01HU | IRS2 Antibody, Biotin conjugated |
Human | ELISA |
IRs2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP011830MO CSB-EP011830MO CSB-BP011830MO CSB-MP011830MO CSB-EP011830MO-B |
Recombinant Mouse Insulin receptor substrate 2 (Irs2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IRs2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP011830HU CSB-EP011830HU CSB-BP011830HU CSB-MP011830HU CSB-EP011830HU-B |
Recombinant Human Insulin receptor substrate 2 (IRS2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Insulin receptor substrate 2 is a protein in humans that is encoded by the IRS2 gene. The IRS2 protein is a cytoplasmic signaling molecule that mediates the effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. IRS2 is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. Mice lacking IRS2 have a diabetic phenotype as well as a 40% reduction in brain mass. IRS2 may mediate the control of various cellular processes by insulin.