PDGFRB, or platelet-derived growth factor receptor beta, is a transmembrane receptor tyrosine kinase encoded by the PDGFRB gene and mainly expressed in tissues like the kidney, lung, and digestive system. It activates downstream signal transduction pathways such as PI3K/AKT and RAS/RAF/MEK/ERK by binding with its ligand platelet-derived growth factor, regulating cell proliferation, differentiation, migration, and survival. PDGFRB is involved in physiological processes like angiogenesis, organ development, and wound healing, and its dysfunction is associated with diseases such as certain cancers and vascular diseases.
Recombinant Human Platelet-derived growth factor receptor beta (PDGFRB), partial (CSB-EP017713HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
PDGFRB Recombinant Monoclonal Antibody (CSB-RA213932A0HU)
Validated Data
IHC image of CSB-RA213932A0HU diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
The following PDGFRB reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PDGFRB Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA017713GA01HU | PDGFRB Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA828739 | PDGFRB (Ab-751) Antibody | Human,Rat | ELISA,WB |
CSB-PA979025 | Phospho-PDGFRB (Tyr740) Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA556830 | PDGFRB (Ab-771) Antibody | Human,Rat | ELISA,WB |
CSB-PA000745 | Phospho-PDGFRB (Y1021) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA003726 | PDGFRB Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA004625 | PDGFRB Antibody | Human,Rat | WB, ELISA |
CSB-PA030005 | Phospho-PDGFRB (Y771) Antibody | Human,Rat | WB, ELISA |
CSB-PA030006 | Phospho-PDGFRB (Y740) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA030007 | Phospho-PDGFRB (Y751) Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
CSB-PA030008 | PDGFRB Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
CSB-PA030009 | PDGFRB Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA030010 | PDGFRB Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA208206 | PDGFRB Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA266610 | PDGFRB Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA017713LA01HU | PDGFRB Antibody | Human | ELISA, IHC, IF |
CSB-PA017713LD01HU | PDGFRB Antibody, Biotin conjugated | Human | ELISA |
CSB-PA017713LC01HU | PDGFRB Antibody, FITC conjugated | Human | |
CSB-PA017713LB01HU | PDGFRB Antibody, HRP conjugated | Human | ELISA |
CSB-RA017713A740phHU | Phospho-PDGFRB (Y740) Recombinant Monoclonal Antibody | Human | ELISA, WB |
CSB-RA213932A0HU | PDGFRB Recombinant Monoclonal Antibody | Human | ELISA, IHC |
PDGFRB Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP017713MO CSB-EP017713MO CSB-BP017713MO CSB-MP017713MO CSB-EP017713MO-B |
Recombinant Mouse Platelet-derived growth factor receptor beta (Pdgfrb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PDGFRB Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP017713HU CSB-BP017713HU CSB-MP017713HU CSB-EP017713HU-B |
Recombinant Human Platelet-derived growth factor receptor beta (PDGFRB), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP017713HU | Recombinant Human Platelet-derived growth factor receptor beta (PDGFRB), partial | E.coli |
PDGFRB Proteins for Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Code | Product Name | Source |
---|---|---|
CSB-YP304446TKY CSB-EP304446TKY CSB-BP304446TKY CSB-MP304446TKY CSB-EP304446TKY-B |
Recombinant Takifugu rubripes Platelet-derived growth factor receptor beta (pdgfrb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PDGFRB Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
Code | Product Name | Source |
---|---|---|
CSB-YP764838DO CSB-EP764838DO CSB-BP764838DO CSB-MP764838DO CSB-EP764838DO-B |
Recombinant Dog Platelet-derived growth factor receptor beta (PDGFRB), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PDGFRB ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL017713HU | Human Beta-type platelet-derived growth factor receptor(PDGFRB) ELISA kit | serum, plasma, tissue homogenates | 15.6 pg/mL |
PDGFRB ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL017713MO | Mouse Beta-type platelet-derived growth factor receptor(PDGFRB) ELISA kit |