Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform is a protein in humans that is encoded by PIK3CB gene. Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Involved in the activation of AKT1 upon stimulation by G-protein coupled receptors (GPCRs) ligands such as CXCL12, sphingosine 1-phosphate, and lysophosphatidic acid. May also act downstream receptor tyrosine kinases. Required in different signaling pathways for stable platelet adhesion and aggregation.

PIK3CB Antibodies

PIK3CB Antibodies for Homo sapiens (Human)

Code Product Name Species Reactivity Application
CSB-PA017999GA01HU PIK3CB Antibody Human ELISA,WB
CSB-PA110424 PIK3CB Antibody Human,Mouse,Rat ELISA,IHC
CSB-PA017999LA01HU PIK3CB Antibody Human ELISA, IF
CSB-PA017999LB01HU PIK3CB Antibody, HRP conjugated Human ELISA
CSB-PA017999LC01HU PIK3CB Antibody, FITC conjugated Human ELISA
CSB-PA017999LD01HU PIK3CB Antibody, Biotin conjugated Human ELISA


PIK3CB cDNA for Mus musculus (Mouse)

Code Product Name Vector Accession NO.
CSB-CL806903MO Pik3cb pUC NM_029094.3

PIK3CB cDNA for Homo sapiens (Human)

Code Product Name Vector Accession NO.
CSB-CL017999HU1 PIK3CB pUC NM_006219.2


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