Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform is a protein in humans that is encoded by PIK3CB gene. Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Involved in the activation of AKT1 upon stimulation by G-protein coupled receptors (GPCRs) ligands such as CXCL12, sphingosine 1-phosphate, and lysophosphatidic acid. May also act downstream receptor tyrosine kinases. Required in different signaling pathways for stable platelet adhesion and aggregation.
PIK3CB Antibodies for Homo sapiens (Human)
|Code||Product Name||Species Reactivity||Application|
|CSB-PA017999LA01HU||PIK3CB Antibody||Human||ELISA, IF|
|CSB-PA017999LB01HU||PIK3CB Antibody, HRP conjugated||Human||ELISA|
|CSB-PA017999LC01HU||PIK3CB Antibody, FITC conjugated||Human||ELISA|
|CSB-PA017999LD01HU||PIK3CB Antibody, Biotin conjugated||Human||ELISA|
PIK3CB Proteins for Homo sapiens (Human)
|Recombinant Human Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(PIK3CB) ,partial|| Yeast
PIK3CB Proteins for Mus musculus (Mouse)
|Recombinant Mouse Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Pik3cb) ,partial|| Yeast
Join the 25,000 subscribers to get research hotpots, technical tips, latest information on events, sales and offers.
Sign up now!
We don't deal in spam.