Mothers against decapentaplegic homolog 7 is a protein in humans that is encoded by SMAD7 gene. Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

SMAD7 Antibodies

SMAD7 Antibodies for Homo sapiens (Human)

SMAD7 Proteins

SMAD7 Proteins for Homo sapiens (Human)

SMAD7 Proteins for Mus musculus (Mouse)

SMAD7 Proteins for Rattus norvegicus (Rat)


SMAD7 ELISA Kit for Homo sapiens (Human)

SMAD7 ELISA Kit for Rattus norvegicus (Rat)


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