Tumor necrosis factor receptor superfamily member 10A is a protein in humans that is encoded by TNFRSF10A gene. Receptor for the cytotoxic ligand TNFSF10/TRAIL
The following TNFRSF10A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TNFRSF10A Antibodies for Homo sapiens (Human)
|Code||Product Name||Species Reactivity||Application|
|Human,Monkey||WB, IF, ELISA|
|Human||ELISA, WB, IHC, IF, IP|
TNFRSF10A Antibody, HRP conjugated
TNFRSF10A Antibody, FITC conjugated
TNFRSF10A Antibody, Biotin conjugated
TNFRSF10A Proteins for Homo sapiens (Human)
Recombinant Human Tumor necrosis factor receptor superfamily member 10A(TNFRSF10A)
|in vitro E.coli expression system|
Recombinant Human Tumor necrosis factor receptor superfamily member 10A(TNFRSF10A),partial
In Vivo Biotinylation in E.coli
Tumor necrosis factor receptor superfamily member 10A is a protein in humans that is encoded by the TNFRSF10A gene. It is a member of the TNF-receptor superfamily. TNFRSF10A is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis, thus transduces cell death signal and induces cell apoptosis. It also promotes the activation of NF-kappa-B. Studies with FADD-deficient mice suggested that FADD, a death domain-containing adaptor protein, is required for the apoptosis mediated by this protein.