Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
Tumor necrosis factor receptor superfamily member 10A is a protein in humans that is encoded by TNFRSF10A gene. Receptor for the cytotoxic ligand TNFSF10/TRAIL
The following TNFRSF10A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TNFRSF10A Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA199651 | TNFRSF10A Antibody |
Human | ELISA,WB |
| CSB-PA002191 | TNFRSF10A Antibody |
Human,Monkey | WB, IF, ELISA |
| CSB-PA023964LA01HU | TNFRSF10A Antibody |
Human | ELISA, WB, IHC, IF, IP |
| CSB-PA023964LB01HU | TNFRSF10A Antibody, HRP conjugated |
Human | ELISA |
| CSB-PA023964LC01HU | TNFRSF10A Antibody, FITC conjugated |
Human | |
| CSB-PA023964LD01HU | TNFRSF10A Antibody, Biotin conjugated |
Human | ELISA |
TNFRSF10A Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-CF023964HU | Recombinant Human Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) |
in vitro E.coli expression system |
| CSB-YP023964HU1 CSB-EP023964HU1 CSB-BP023964HU1 CSB-MP023964HU1 CSB-EP023964HU1-B |
Recombinant Human Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Tumor necrosis factor receptor superfamily member 10A is a protein in humans that is encoded by the TNFRSF10A gene. It is a member of the TNF-receptor superfamily. TNFRSF10A is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis, thus transduces cell death signal and induces cell apoptosis. It also promotes the activation of NF-kappa-B. Studies with FADD-deficient mice suggested that FADD, a death domain-containing adaptor protein, is required for the apoptosis mediated by this protein.
