Z-DNA-binding protein 1 is a protein in humans that is encoded by ZBP1 gene. Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even host origin. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor (IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3 (By similarity).
The following Zbp1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
Zbp1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA026311GA01HU | ZBP1 Antibody |
Human | ELISA,WB,IHC |
Zbp1 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP837712RA CSB-EP837712RA CSB-BP837712RA CSB-MP837712RA CSB-EP837712RA-B |
Recombinant Rat Z-DNA-binding protein 1 (Zbp1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Zbp1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP861990HU CSB-EP861990HU CSB-BP861990HU CSB-MP861990HU CSB-EP861990HU-B |
Recombinant Human Z-DNA-binding protein 1 (ZBP1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Zbp1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP865587MO CSB-EP865587MO CSB-BP865587MO CSB-MP865587MO CSB-EP865587MO-B |
Recombinant Mouse Z-DNA-binding protein 1 (Zbp1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |