Recombinant Human C-X-C motif chemokine 5 protein(CXCL5) (Active)

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Code CSB-AP000681HU
Product Type Chemokine
Size US$112Purchase it in Cusabio online store
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Uniprot No. P42830
Lead Time 5-10 business days
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Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias ENA-78, Epithelial-derived neutrophil-activating protein 78, Neutrophil-activating peptide ENA-78, Small-inducible cytokine B5
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration of 5.0-10 ng/ml.
Purity >97% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence AAVLRELRCV CLQTTQGVHP KMISNLQVFA IGPQCSKVEV VASLKNGKEI CLDPEAPFLK KVIQKILDGG NKEN
Research Area Immunology
Source E.coli
Gene Names CXCL5
Expression Region 41-114aa
Tag Info Tag-Free
Mol. Weight 8.1 kDa
Protein Description Partial
PubMed ID 7828901; 7929219; 7999089; 11468158; 15489334; 1744577; 10095777; 12665801; 14711052
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Function Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes.
Subcellular Location Secreted
Protein Families Intercrine alpha (chemokine CxC) family
Database Links

HGNC: 10642

OMIM: 600324

KEGG: hsa:6374

STRING: 9606.ENSP00000296027

UniGene: Hs.89714

Pathway Chemokine signaling pathway
TNF signaling pathway
IL-17 signaling pathway

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