CXCL5, also known as C-X-C motif chemokine ligand 5, is commonly referred to as ENA-78. This protein functions mainly by binding to the CXCR2 receptor. It is involved in the activation of signal - transduction pathways such as the MAPK and PI3K - Akt pathways, regulating cell migration, angiogenesis, and immune cell recruitment.
Studies have shown that CXCL5 is associated with various diseases, including cancer, inflammatory diseases, and cardiovascular disorders. In the field of drug development, targeting CXCL5 and its signaling pathway is considered a promising strategy. Some pre - clinical studies are exploring inhibitors to block its effects, aiming to develop new therapies.
Recombinant Human C-X-C motif chemokine 5 (CXCL5), partial (CSB-EP006250HU1)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-RP061574h could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) CXCL5.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-RP061574h could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) CXCL5.
CXCL5 Antibody (CSB-PA06155A0Rb)
Validated Data
Western blot
All lanes: CXCL5 antibody at 2µg/ml + 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/15000 dilution
Predicted band size: 12 kDa
Observed band size: 90 kDa
Human Epithelial neutrophil activating peptide 78 (ENA-78/CXCL5) ELISA Kit (CSB-E08178h)
Validated Data
Code: CSB-E08178h
Size: 96T,5×96T,10×96T
Sensitivity: 0.567 ng/mL
Detection Range: 0.625 ng/mL-40 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following CXCL5 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CXCL5 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA06155A0Rb | CXCL5 Antibody | Human | ELISA, WB |
CSB-PA06155B0Rb | CXCL5 Antibody, HRP conjugated | Human | ELISA |
CSB-PA006250GA01HU | CXCL5 Antibody | Human | ELISA |
CXCL5 Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA09257A0Rb | Cxcl5 Antibody | Mouse | ELISA, WB |
CSB-PA09257B0Rb | Cxcl5 Antibody, HRP conjugated | Mouse | ELISA |
CSB-PA09257C0Rb | Cxcl5 Antibody, FITC conjugated | Mouse |
CXCL5 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP006250RA CSB-EP006250RA CSB-BP006250RA CSB-MP006250RA CSB-EP006250RA-B |
Recombinant Rat C-X-C motif chemokine 5 (Cxcl5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-AP001431RA | Recombinant Rat C-X-C motif chemokine 5 protein (Cxcl5) (Active) | E.coli |
CXCL5 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP006250HU CSB-EP006250HU CSB-BP006250HU CSB-MP006250HU CSB-EP006250HU-B |
Recombinant Human C-X-C motif chemokine 5 (CXCL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-AP000671HU | Recombinant Human C-X-C motif chemokine 5 (CXCL5), partial (Active) | E.coli |
CSB-AP000681HU | Recombinant Human C-X-C motif chemokine 5 protein (CXCL5), partial (Active) | E.coli |
CSB-EP006250HU1 | Recombinant Human C-X-C motif chemokine 5 (CXCL5), partial | E.coli |
CSB-AP003561HU | Recombinant Human C-X-C motif chemokine 5 (CXCL5), partial (Active) | E.coli |
CSB-EP006250HU1e0 | Recombinant Human C-X-C motif chemokine 5 (CXCL5), partial | E.coli |
CXCL5 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP006250MO CSB-EP006250MO CSB-BP006250MO CSB-MP006250MO CSB-EP006250MO-B |
Recombinant Mouse C-X-C motif chemokine 5 (Cxcl5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-AP001111MO | Recombinant Mouse C-X-C motif chemokine 5 protein (Cxcl5), partial (Active) | E.coli |
CSB-AP001121MO | Recombinant Mouse C-X-C motif chemokine 5 protein (Cxcl5) (Active) | E.Coli |
CSB-EP006250MO1 | Recombinant Mouse C-X-C motif chemokine 5 (Cxcl5), partial | E.coli |
CXCL5 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E08178h | Human Epithelial neutrophil activating peptide 78 (ENA-78/CXCL5) ELISA Kit | serum, plasma, tissue homogenates | 0.567 ng/mL |
CSB-E08178h-IS | Human Epithelial neutrophil activating peptide 78 (ENA-78/CXCL5) ELISA Kit | serum, plasma, tissue homogenates | 23.5 pg/mL |
CXCL5 ELISA Kit for Rattus norvegicus (Rat)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E08179r | Rat Epithelial neutrophil activating peptide 78,ENA-78 ELISA Kit | serum, plasma, tissue homogenates | 0.078 ng/mL |
CXCL5 ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E08180m | Mouse Epithelial neutrophil activating peptide 78,ENA-78 ELISA Kit | serum, plasma, tissue homogenates | 15.6 pg/ml |