cdc42 Antibody

1. Cdc42 activation pattern by GEF1 and Scd1 promotes different events during cytokinesis. PMID: 26941334
2. cells evolved highly robust symmetry-breaking mechanisms that rely on feedback amplification of local Cdc42 activity. In turn, local Cdc42 activity favors Cdc42 accumulation because active Cdc42 is poorly mobile relative to the inactive form. PMID: 26338468
3. Regulation of Cdc42 activity and localization and polarized cell growth in Schizosaccharomyces pombe. [Review] PMID: 24450652
4. REVIEW: Cdc42 dynamics in the control of fission yeast cell polarization PMID: 24256285
5. findings show that feedbacks regulating Cdc42 oscillations and spatial self-organization appear to provide a flexible mechanism for fission yeast cells to explore polarization states and to control their morphology PMID: 22604726
6. The GTPase Rho3 also suppressed cdc42L160S thermosensitivity, restored exocyst localization and AP secretion. PMID: 21899677
7. The Rga4 and the Scd1 establish a gradient of activated Cdc42 within the cellular tip plasma membrane, and it is this gradient that determines cell growth-zone size and normal cell width. PMID: 21849474
8. Studies indicate that Once Cdc42 is polarized to the presumptive bud site, it organizes the actin cytoskeleton, and the polarized secretion to carry out the polarized cell growth. PMID: 20175747
9. Cdc42 regulates Pob1 localization and/or stability. Pob1 interacts with Cdc42. PMID: 19710424

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KEGG: spo:SPAC110.03

STRING: 4896.SPAC110.03.1