CDC42

CDC42 encodes the cell division cycle 42 protein, a member of the Rho GTPase family. Key aliases include G25K and CDC42Hs. It functions as a molecular switch, cycling between active GTP-bound and inactive GDP-bound states to regulate actin cytoskeleton reorganization, cell polarity, and proliferation.
CDC42 participates in signaling pathways such as PI3K/AKT and MAPK, linking extracellular cues to intracellular responses. Dysregulation is associated with cancer metastasis, neurodegenerative disorders, and infectious diseases. Preclinical studies target CDC42 with small-molecule inhibitors and peptide mimetics, exploring therapeutic potential in oncology and inflammatory conditions.

Popular Product:

CDC42 Antibody (CSB-PA005008DA01HU)

Validated Data

Western blot
All lanes: CDC42 antibody at 6µg/ml
Lane 1: Hela whole cell lysate
Lane 2: Jurkat whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 22 kDa
Observed band size: 22 kDa

The following CDC42 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CDC42 Antibodies

CDC42 Proteins

CDC42 Antibodies

CDC42 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA005008GA01HU	CDC42 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA620509	CDC42 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA005008DA01HU	CDC42 Antibody	Human	ELISA, WB
CSB-RA177985A0HU	CDC42 Recombinant Monoclonal Antibody	Human, Mouse	ELISA, WB, IHC

CDC42 Antibodies for Drosophila melanogaster (Fruit fly)

Code	Product Name	Species Reactivity	Application
CSB-PA334771XA01DLU	Cdc42 Antibody	Drosophila melanogaster (Fruit fly)	ELISA, WB (ensure identification of antigen)

CDC42 Antibodies for Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)

Code	Product Name	Species Reactivity	Application
CSB-PA864051XA01DOT	CDC42 Antibody	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)	ELISA, WB (ensure identification of antigen)

CDC42 Antibodies for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA325635XA01SVG	CDC42 Antibody	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ELISA, WB (ensure identification of antigen)

CDC42 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA934486XA01SXV	cdc42 Antibody	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ELISA, WB (ensure identification of antigen)

CDC42 Proteins

CDC42 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP005008MO CSB-BP005008MO CSB-MP005008MO CSB-EP005008MO-B	Recombinant Mouse Cell division control protein 42 homolog (Cdc42)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDC42 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP005008HU CSB-EP005008HU CSB-BP005008HU CSB-EP005008HU-B	Recombinant Human Cell division control protein 42 homolog (CDC42)	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli

CDC42 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP005008DO CSB-EP005008DO CSB-BP005008DO CSB-MP005008DO CSB-EP005008DO-B	Recombinant Dog Cell division control protein 42 homolog (CDC42)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDC42 Proteins for Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

Code	Product Name	Source
CSB-YP005008CZD CSB-EP005008CZD CSB-BP005008CZD CSB-MP005008CZD CSB-EP005008CZD-B	Recombinant Candida albicans Cell division control protein 42 homolog (CDC42)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDC42 Proteins for Candida albicans (strain WO-1) (Yeast)

Code	Product Name	Source
CSB-YP005008CZE CSB-EP005008CZE CSB-BP005008CZE CSB-MP005008CZE CSB-EP005008CZE-B	Recombinant Candida albicans Cell division control protein 42 homolog (CDC42)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDC42 Proteins for Colletotrichum gloeosporioides (Anthracnose fungus) (Glomerella cingulata)

Code	Product Name	Source
CSB-YP005008DVE CSB-EP005008DVE CSB-BP005008DVE CSB-MP005008DVE CSB-EP005008DVE-B	Recombinant Colletotrichum gloeosporioides Cell division control protein 42 homolog (CDC42)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDC42 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Source
CSB-YP325635SVG CSB-EP325635SVG CSB-BP325635SVG CSB-MP325635SVG CSB-EP325635SVG-B	Recombinant Saccharomyces cerevisiae Cell division control protein 42 (CDC42)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDC42 Proteins for Drosophila melanogaster (Fruit fly)

Code	Product Name	Source
CSB-YP334771DLU CSB-EP334771DLU CSB-BP334771DLU CSB-MP334771DLU CSB-EP334771DLU-B	Recombinant Drosophila melanogaster Cdc42 homolog (Cdc42)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDC42 Proteins for Anopheles gambiae (African malaria mosquito)

Code	Product Name	Source
CSB-YP619125BZL CSB-EP619125BZL CSB-BP619125BZL CSB-MP619125BZL CSB-EP619125BZL-B	Recombinant Anopheles gambiae Cdc42 homolog (Cdc42)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDC42 Proteins for Aedes aegypti (Yellowfever mosquito) (Culex aegypti)

Code	Product Name	Source
CSB-YP621019AXQ CSB-EP621019AXQ CSB-BP621019AXQ CSB-MP621019AXQ CSB-EP621019AXQ-B	Recombinant Aedes aegypti Cdc42 homolog (Cdc42)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDC42 Proteins for Drosophila pseudoobscura pseudoobscura (Fruit fly)

Code	Product Name	Source
CSB-YP642785DME CSB-EP642785DME CSB-BP642785DME CSB-MP642785DME CSB-EP642785DME-B	Recombinant Drosophila pseudoobscura pseudoobscura Cdc42 homolog (Cdc42)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDC42 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP644437BO CSB-EP644437BO CSB-BP644437BO CSB-MP644437BO CSB-EP644437BO-B	Recombinant Bovine Cell division control protein 42 homolog (CDC42)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDC42 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-YP680988MOV CSB-EP680988MOV CSB-BP680988MOV CSB-MP680988MOV CSB-EP680988MOV-B	Recombinant Macaca fascicularis Cell division control protein 42 homolog (CDC42)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDC42 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP806532RA CSB-EP806532RA CSB-BP806532RA CSB-MP806532RA CSB-EP806532RA-B	Recombinant Rat Cell division control protein 42 homolog (Cdc42)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDC42 Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP835458CH CSB-EP835458CH CSB-BP835458CH CSB-MP835458CH CSB-EP835458CH-B	Recombinant Chicken Cell division control protein 42 homolog (CDC42)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDC42 Proteins for Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)

Code	Product Name	Source
CSB-YP864051DOT CSB-EP864051DOT CSB-BP864051DOT CSB-MP864051DOT CSB-EP864051DOT-B	Recombinant Ashbya gossypii Cell division control protein 42 (CDC42)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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