Code | CSB-PA004957LA01HU |
Size | US$299 |
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Full Product Name | Rabbit anti-Homo sapiens (Human) CD79A Polyclonal antibody | ||||||
Uniprot No. | P11912 | ||||||
Target Names | CD79A | ||||||
Alternative Names |
CD79A; IGA; MB1; B-cell antigen receptor complex-associated protein alpha chain; Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein; CD antigen CD79a
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Raised in | Rabbit | ||||||
Species Reactivity | Human | ||||||
Immunogen | Recombinant Human B-cell antigen receptor complex-associated protein alpha chain protein (70-142AA) | ||||||
Immunogen Species | Homo sapiens (Human) | ||||||
Conjugate | Non-conjugated The CD79A Antibody (Product code: CSB-PA004957LA01HU) is Non-conjugated. For CD79A Antibody with conjugates, please check the following table. |
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Clonality | Polyclonal | ||||||
Isotype | IgG | ||||||
Purification Method | >95%, Protein G purified | ||||||
Concentration | It differs from different batches. Please contact us to confirm it. | ||||||
Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
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Form | Liquid | ||||||
Tested Applications | ELISA, IHC, IF | ||||||
Recommended Dilution |
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Protocols | ELISA Protocol Immunohistochemistry (IHC) Protocol Immunofluorescence (IF) Protocol |
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Troubleshooting and FAQs | Antibody FAQs | ||||||
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||
Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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Function |
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
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Gene References into Functions |
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Involvement in disease | Agammaglobulinemia 3, autosomal recessive (AGM3) |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | B-cells. |
Database Links |
HGNC: 1698 OMIM: 112205 KEGG: hsa:973 STRING: 9606.ENSP00000221972 UniGene: Hs.631567 |