Cleaved-KLKB1 (R390) Antibody

Code CSB-PA000082
Size US$167
Uniprot No. P03952
  • Western Blot analysis of HeLa cells using Cleaved-Plasma Kallikrein HC (R390) Polyclonal Antibody
  • Western Blot analysis of VEC cells using Cleaved-Plasma Kallikrein HC (R390) Polyclonal Antibody
Protocols Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol
Immunogen Synthesized peptide derived from the Internal region of Human Plasma Kallikrein HC.
Raised in Rabbit
Species Reactivity Human
Tested Applications WB,IHC,ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/10000
Form Liquid
Conjugate Non-conjugated
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Alias KLKB1; KLK3; Plasma kallikrein; Fletcher factor; Kininogenin; Plasma prekallikrein
Immunogen Species Homo sapiens (Human)
Target Names KLKB1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
Involvement in disease Prekallikrein deficiency (PKK deficiency)
Subcellular Location Secreted
Protein Families Peptidase S1 family, Plasma kallikrein subfamily
Database Links

HGNC: 6371

OMIM: 229000

KEGG: hsa:3818

STRING: 9606.ENSP00000264690

UniGene: Hs.237642

Pathway Complement and coagulation cascades

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