IL31 Antibody

Datasheet
Code CSB-PA239746
Size US$299
Uniprot No. Q6EBC2
Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA239746(IL31 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA239746(IL31 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human placenta tissue, Primary antibody: CSB-PA239746(IL31 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
Immunogen Synthetic peptide of Human IL31
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA,WB,IHC;ELISA:1:1000-1:2000,WB:1:200-1:1000,IHC:1:25-1:100
Relevance IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma.
Form Liquid
Conjugate Non-conjugated
Storage Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method Antigen affinity purification
Isotype IgG
Alias interleukin 31
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Target Names IL31
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR
Subcellular Location Secreted
Tissue Specificity Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea.
Database Links

HGNC: 19372

OMIM: 609509

KEGG: hsa:386653

STRING: 9606.ENSP00000366234

UniGene: Hs.569071

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