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| Code | CSB-PA17347A0Rb |
| See More Details |  |
| Size | US$299 |
| Uniprot No. | P10749 |
| Protocols | ELISA Protocol |
| Immunogen | Recombinant Mouse Interleukin-1 beta protein (119-268AA) |
| Raised in | Rabbit |
| Species Reactivity | Mouse |
| Tested Applications | ELISA |
| Relevance | Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. |
| Form | Liquid |
| Conjugate | Non-conjugated |
| Storage Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method | >95%, Protein G purified |
| Isotype | IgG |
| Clonality | Polyclonal |
| Alias | Interleukin-1 beta (IL-1 beta), Il1b |
| Immunogen Species | Mouse |
| Research Area | Immunology |
| Target Names | Il1b |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
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| Function | Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. |
| Subcellular Location | Cytoplasm, cytosol, Lysosome, Secreted, exosome, Cytoplasmic vesicle, autophagosome, Secreted |
| Protein Families | IL-1 family |
| Tissue Specificity | Expressed in activated macrophages (at protein level). |
| Database Links |
KEGG: mmu:16176 STRING: 10090.ENSMUSP00000028881 UniGene: Mm.222830 |
| Pathway |
MAPK signaling pathway
Lipids and Inflammation in Atherogenesis NF-kappa B signaling pathway TNF signaling pathway Necroptosis Hematopoietic cell lineage IL-17 signaling pathway Inflammasome Signaling NOD-like receptor signaling pathway Osteoclast differentiation Th17 cell differentiation Toll-like receptor signaling pathway AGE-RAGE signaling pathway in diabetic complications Excitatory synapse pathway |
Il1b Antibodies for Mouse
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA17347D0Rb | Il1b Antibody, Biotin conjugated | Mouse | ELISA |
| CSB-PA17347B0Rb | Il1b Antibody, HRP conjugated | Mouse | ELISA |
| CSB-PA17347C0Rb | Il1b Antibody, FITC conjugated | Mouse | ELISA |
Il1b Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-AP004731MO | Recombinant Mouse Interleukin-1 beta(Il1b) (Active) | E.coli |
| CSB-YP011614MO CSB-EP011614MO CSB-BP011614MO CSB-MP011614MO |
Recombinant Mouse Interleukin-1 beta(Il1b) | Yeast E.coli Baculovirus Mammalian cell |
| CSB-AP003261MO | Recombinant Mouse Interleukin-1 beta protein(Il1b) (Active) | E.coli |
| CSB-RP173474m | Recombinant Mouse Interleukin-1 beta(Il1b),partial | E.coli |
Il1b ELISA Kit for Mus musculus (Mouse)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E08054m | Mouse Interleukin 1β,IL-1β ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 7.8 pg/mL |
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