TGFB3 Antibody

Datasheet
Code CSB-PA217147
Product Type Polyclonal Antibody
Former Code(s) CSB-PA044236
Size US$297
Uniprot No. P10600
Image
  • Western blot analysis of extracts from COS7 cells, using TGF β3 antibody.
  • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using TGF β3 antibody.
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Synthesized peptide derived from Human TGF β3.
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Specificity The antibody detects endogenous levels of total TGF β3 protein.
Tested Applications ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:100
Relevance Involved in embryogenesis and cell differentiation.

Brian C. McKaig, Am J Physiol Gastrointest Liver Physiol, May 1999; 276: 1087.
Nasser Chegini, Hum. Reprod., Jun 2001; 16: 1291 - 1300.
Y Taya, Development, Sep 1999; 126: 3869.
C Gordon-Thomson, Invest. Ophthalmol. Vis. Sci., Jul 1998; 39: 1399.
Form Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality Polyclonal
Alias TRANSFORMING GROWTH FACTOR BETA-3;
Immunogen Species Homo sapiens (Human)
Target Names TGFB3
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Involved in embryogenesis and cell differentiation.
Involvement in disease Arrhythmogenic right ventricular dysplasia, familial, 1 (ARVD1); Loeys-Dietz syndrome 5 (LDS5)
Subcellular Location Secreted
Protein Families TGF-beta family
Database Links

HGNC: 11769

OMIM: 107970

KEGG: hsa:7043

STRING: 9606.ENSP00000238682

UniGene: Hs.592317

Pathway Hippo signaling pathway
MAPK signaling pathway
TGF-beta signaling pathway
Cell cycle
Cellular senescence
AGE-RAGE signaling pathway in diabetic complications
FoxO signaling pathway

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