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| Code | CSB-PA004324 |
| Size | US$167 |
| Uniprot No. | Q13114 |
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| Immunogen | Synthesized peptide derived from the Internal region of Human TRAF3. |
| Raised in | Rabbit |
| Species Reactivity | Human,Mouse |
| Tested Applications | WB,ELISA;WB:1/500-1/2000.IHC:1/200-1/1000.ELISA:1/10000 |
| Form | Liquid |
| Conjugate | Non-conjugated |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Isotype | IgG |
| Alias | TRAF3; CAP1; CRAF1; TNF receptor-associated factor 3; CAP-1; CD40 receptor-associated factor 1; CRAF1; CD40-binding protein; CD40BP; LMP1-associated protein 1; LAP1 |
| Immunogen Species | Homo sapiens (Human) |
| Protocols | Western Blotting(WB) Protocol ELISA Protocol |
| Target Names | TRAF3 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote 'Lys-63'-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimulation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regulates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B. Promotes ubiquitination and proteasomal degradation of MAP3K14. |
| Involvement in disease | Herpes simplex encephalitis 3 (HSE3) |
| Subcellular Location | Cytoplasm, Endosome, Mitochondrion |
| Protein Families | TNF receptor-associated factor family, A subfamily |
| Database Links |
HGNC: 12033 OMIM: 601896 KEGG: hsa:7187 STRING: 9606.ENSP00000376500 UniGene: Hs.510528 |
| Pathway |
NF-kappa B signaling pathway
TNF signaling pathway IL-17 signaling pathway NOD-like receptor signaling pathway Toll-like receptor signaling pathway |
TRAF3 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA024148GA01HU | TRAF3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA024148LC01HU | TRAF3 Antibody, FITC conjugated | Human | ELISA |
| CSB-PA594760 | TRAF3 Antibody | Human | ELISA,WB,IHC |
| CSB-PA940722 | TRAF3 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA024148LD01HU | TRAF3 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA024148LB01HU | TRAF3 Antibody, HRP conjugated | Human | ELISA |
TRAF3 Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA024148LA01HU | TRAF3 Antibody | Human | ELISA, WB, IF |
TRAF3 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP024148HU CSB-EP024148HU CSB-BP024148HU CSB-MP024148HU |
Recombinant Human TNF receptor-associated factor 3(TRAF3) | Yeast E.coli Baculovirus Mammalian cell |
2-hydroxyisobutyryl-HIST1H1C (K116) Antibody
Applications: ELISA, ICC, IF, ChIP
Species Reactivity: Human
2-hydroxyisobutyryl-HIST1H2BC (K24) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human
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