TRAF3

TNF receptor-associated factor 3 is a protein in humans that is encoded by TRAF3 gene. Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote 'Lys-63'-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimulation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regulates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B.

TRAF3 Antibodies

TRAF3 Antibodies for Homo sapiens (Human)

TRAF3 Antibodies for Human

TRAF3 Proteins

TRAF3 Proteins for Mus musculus (Mouse)

TRAF3 Proteins for Homo sapiens (Human)

TRAF3 cDNA for Homo sapiens (Human)

Code Product Name Vector Accession NO.
CSB-CL024148HU1 TRAF3 pUC NM_001199427.1
CSB-CL024148HU2 TRAF3 pUC NM_003300.3
CSB-CL024148HU3 TRAF3 pUC NM_145725.2
CSB-CL024148HU4 TRAF3 pUC NM_145726.2

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