TNF receptor-associated factor 3 is a protein in humans that is encoded by TRAF3 gene. Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote 'Lys-63'-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimulation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regulates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B.

TRAF3 Antibodies

TRAF3 Antibodies for Homo sapiens (Human)

Code Product Name Species Reactivity Application
CSB-PA024148GA01HU TRAF3 Antibody Human,Mouse,Rat ELISA,WB
CSB-PA004324 TRAF3 Antibody Human,Mouse WB,ELISA
CSB-PA594760 TRAF3 Antibody Human ELISA,WB,IHC
CSB-PA940722 TRAF3 Antibody Human,Mouse ELISA,WB,IHC
CSB-PA024148LB01HU TRAF3 Antibody, HRP conjugated Human ELISA
CSB-PA024148LC01HU TRAF3 Antibody, FITC conjugated Human ELISA
CSB-PA024148LD01HU TRAF3 Antibody, Biotin conjugated Human ELISA

TRAF3 Antibodies for Human

Code Product Name Species Reactivity Application
CSB-PA024148LA01HU TRAF3 Antibody Human ELISA, IF


TRAF3 cDNA for Homo sapiens (Human)

Code Product Name Vector Accession NO.
CSB-CL024148HU1 TRAF3 pUC NM_001199427.1
CSB-CL024148HU2 TRAF3 pUC NM_003300.3
CSB-CL024148HU3 TRAF3 pUC NM_145725.2
CSB-CL024148HU4 TRAF3 pUC NM_145726.2


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