TRAF3 Research Reagents

TNF receptor-associated factor 3 is a protein in humans that is encoded by TRAF3 gene. Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote 'Lys-63'-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimulation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regulates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B.

The following TRAF3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TRAF3 Antibodies

TRAF3 Antibodies for Homo sapiens (Human)

TRAF3 Proteins

TRAF3 Proteins for Mus musculus (Mouse)

TRAF3 Proteins for Homo sapiens (Human)

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