Code | CSB-EP014597HU |
Abbreviation | Recombinant Human MKI67 protein, partial |
MSDS | |
Size | $224 |
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Amino acids 3120-3256 form the expressed segment for recombinant Human MKI67. The calculated molecular weight for this MKI67 protein is 19.4 kDa. The MKI67 protein was expressed in e.coli. The MKI67 gene fragment has been modified by fusing the N-terminal 6xHis tag, providing convenience in detecting and purifying the recombinant MKI67 protein during the following stages.
The human proliferation marker protein Ki-67, encoded by the MKI67 gene, is a widely utilized marker for cellular proliferation. Ki-67 is present during all active phases of the cell cycle (G1, S, G2, and mitosis) but absent in the resting phase (G0). It serves as a nuclear marker for assessing and quantifying the proliferative activity of cells, playing a crucial role in cancer diagnosis and prognosis. Researchers often employ Ki-67 immunohistochemistry to evaluate the growth fraction of tumors and determine their aggressiveness. Beyond cancer research, Ki-67 is also explored in studies related to cell cycle regulation, apoptosis, and various physiological and pathological processes associated with cell proliferation.There are currently no reviews for this product.