Your Good Partner in Biology Research
Tel : 301-363-4651
Your Good Partner in Biology Research
| Product Type | Recombinant Protein |
| Uniprot No. | P11215 |
| Species | Homo sapiens (Human) |
| Gene Names | ITGAM |
| Protein Names | Recommended name: Integrin alpha-M Alternative name(s): CD11 antigen-like family member B CR-3 alpha chain Cell surface glycoprotein MAC-1 subunit alpha Leukocyte adhesion receptor MO1 Neutrophil adherence receptor CD_antigen= |
| Storage | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
| Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
| Function | Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration |
| Involvement in disease | Systemic lupus erythematosus 6 (SLEB6) |
| Subcellular Location | Cell membrane, Single-pass type I membrane protein, Membrane raft, Single-pass type I membrane protein |
| Protein Families | Integrin alpha chain family |
| Tissue Specificity | Predominantly expressed in monocytes and granulocytes (PubMed:1346576). Expressed in neutrophils (at protein level) (PubMed:21193407). |
| Database Links |
HGNC: 6149 OMIM: 120980 KEGG: hsa:3684 STRING: 9606.ENSP00000441691 UniGene: Hs.172631 |
| Pathway |
Regulation of actin cytoskeleton
Complement and coagulation cascades Hematopoietic cell lineage Leukocyte transendothelial migration Rap1 signaling pathway |
| Product Name | Recombinant Human Integrin alpha-M(ITGAM) ,partial,Yeast |
| Code | CSB-YP011876HU |
| Size | Pls inquiry other sizes |
| Source | Yeast |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Protein Description | Partial |
| Storage Buffer | Tris-based buffer,50% glycerol |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Product Name | Recombinant Human Integrin alpha-M(ITGAM) ,partial,E.coli |
| Code | CSB-EP011876HU |
| Size | Pls inquiry other sizes |
| Source | E.coli |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged and C-terminal Myc-tagged N-terminal His-SUMO-tagged and C-terminal Myc-tagged N-terminal His-B2M-tagged and C-terminal Myc-tagged N-terminal His-GST-tagged and C-terminal Myc-tagged N-terminal His-tagged N-terminal His-SUMO-tagged N-terminal His-B2M-tagged N-terminal His-GST-tagged N-terminal GST-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Protein Description | Partial |
| Storage Buffer | Tris-based buffer,50% glycerol |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Product Name | Recombinant Human Integrin alpha-M(ITGAM) ,partial,Baculovirus |
| Code | CSB-BP011876HU |
| Size | Pls inquiry other sizes |
| Source | Baculovirus |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged and C-terminal Myc-tagged N-terminal His-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Protein Description | Partial |
| Storage Buffer | Tris-based buffer,50% glycerol |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Product Name | Recombinant Human Integrin alpha-M(ITGAM) ,partial,Mammalian cell |
| Code | CSB-MP011876HU |
| Size | Pls inquiry other sizes |
| Source | Mammalian cell |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged and C-terminal Myc-tagged N-terminal His-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Protein Description | Partial |
| Storage Buffer | Tris-based buffer,50% glycerol |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
ITGAM Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA148981 | ITGAM Antibody | Human | ELISA,IHC |
| CSB-PA073350 | ITGAM Antibody | Human | ELISA,IHC |
ITGAM Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA011876LA01HU | ITGAM Antibody | Human | ELISA, IHC, IF |
| CSB-PA011876LB01HU | ITGAM Antibody, HRP conjugated | Human | ELISA |
| CSB-PA011876LC01HU | ITGAM Antibody, FITC conjugated | Human | ELISA |
| CSB-PA011876LD01HU | ITGAM Antibody, Biotin conjugated | Human | ELISA |
ITGAM ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E11638h | Human Integrin αM,ITG/CD11b ELISA Kit | serum, plasma, tissue homogenates | 0.195 ng/mL |
Recombinant Mpuse T-cell surface glycoprotein CD3 epsilon chain(Cd3e),partial
Express system: Yeast
Species: Mus musculus (Mouse)
Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 8(CEACAM8)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human ATP synthase subunit alpha, mitochondrial(ATP5F1A)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Rabbit Tropomyosin alpha-1 chain(TPM1)
Express system: Yeast
Species: Oryctolagus cuniculus (Rabbit)
Recombinant Human T-cell surface glycoprotein CD8 alpha chain(CD8A),partial
Express system: Yeast
Species: Homo sapiens (Human)
Wait!
Join the 20,000 subscribers to get research hotpots, technical tips, latest information on events, sales and offers.
Sign up now to get your $50 coupon for protein expression service!
We don't deal in spam.