CHRM1

CHRM1, the muscarinic acetylcholine receptor 1, is a G protein-coupled receptor encoded by the CHRM1 gene and expressed in the central nervous system, retina, and urinary system. It binds to acetylcholine, activating G protein, which inhibits adenylate cyclase activity and promotes phosphoinositide degradation, regulating potassium channels and mediating cellular responses. CHRM1 is involved in regulating bronchoconstriction, gastrointestinal acid secretion, and cognitive function, with its dysfunction associated with diseases like Lambert-Eaton myasthenia syndrome, asthma, and Alzheimer's disease.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CHRM1 Antibody (CSB-PA576885)

Validated Data

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA576885(CHRM1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA576885(CHRM1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)

The following CHRM1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CHRM1 Antibodies

CHRM1 Proteins

CHRM1 ELISA Kits

CHRM1 Antibodies

CHRM1 Antibodies for Rattus norvegicus (Rat)

Code	Product Name	Species Reactivity	Application
CSB-PA005381HA01RA	Chrm1 Antibody	Rat	ELISA, WB

CHRM1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA006806	CHRM1 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA759611	CHRM1 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA576885	CHRM1 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA005381PA01HU	CHRM1 Antibody	Human	ELISA, IF
CSB-PA005381PD01HU	CHRM1 Antibody, Biotin conjugated	Human	ELISA

CHRM1 Proteins

CHRM1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-EP005381RA	Recombinant Rat Muscarinic acetylcholine receptor M1 (Chrm1), partial	E.coli
CSB-YP005381RA	Recombinant Rat Muscarinic acetylcholine receptor M1 (Chrm1), partial	Yeast
CSB-BP005381RA CSB-MP005381RA CSB-EP005381RA-B	Recombinant rat Muscarinic acetylcholine receptor M1	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHRM1 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code	Product Name	Source
CSB-CF712902PYX	Recombinant Pongo abelii Muscarinic acetylcholine receptor M1 (CHRM1)	in vitro E.coli expression system
CSB-YP712902PYX1 CSB-EP712902PYX1 CSB-BP712902PYX1 CSB-MP712902PYX1 CSB-EP712902PYX1-B	Recombinant Pongo abelii Muscarinic acetylcholine receptor M1 (CHRM1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHRM1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-CF005381HU	Recombinant Human Muscarinic acetylcholine receptor M1 (CHRM1)	in vitro E.coli expression system
CSB-YP005381HU1 CSB-BP005381HU1 CSB-MP005381HU1 CSB-EP005381HU1-B	Recombinant Human Muscarinic acetylcholine receptor M1 (CHRM1), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP005381HU1	Recombinant Human Muscarinic acetylcholine receptor M1 (CHRM1), partial	E.coli

CHRM1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-CF005381MO	Recombinant Mouse Muscarinic acetylcholine receptor M1 (Chrm1)	in vitro E.coli expression system
CSB-YP005381MO1 CSB-EP005381MO1 CSB-BP005381MO1 CSB-MP005381MO1 CSB-EP005381MO1-B	Recombinant Mouse Muscarinic acetylcholine receptor M1 (Chrm1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHRM1 Proteins for Macaca mulatta (Rhesus macaque)

Code	Product Name	Source
CSB-CF005381MOW	Recombinant Macaca mulatta (Rhesus macaque) Muscarinic acetylcholine receptor M1 (CHRM1)	in vitro E.coli expression system
CSB-YP005381MOW1 CSB-EP005381MOW1 CSB-BP005381MOW1 CSB-MP005381MOW1 CSB-EP005381MOW1-B	Recombinant Macaca mulatta (Rhesus macaque) Muscarinic acetylcholine receptor M1 (CHRM1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHRM1 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-CF005381PI	Recombinant Pig Muscarinic acetylcholine receptor M1 (CHRM1)	in vitro E.coli expression system
CSB-YP005381PI1 CSB-EP005381PI1 CSB-BP005381PI1 CSB-MP005381PI1 CSB-EP005381PI1-B	Recombinant Pig Muscarinic acetylcholine receptor M1 (CHRM1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHRM1 ELISA Kit

CHRM1 ELISA Kit for Rattus norvegicus (Rat)

Code	Product Name	Sample Types	Sensitivity
CSB-EL005381RA	Rat Muscarinic acetylcholine receptor M1(CHRM1) ELISA kit	serum, plasma, tissue homogenates, cell lysates.	0.27 ng/ml

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CHRM1

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