Cartilage oligomeric matrix protein is a protein in humans that is encoded by COMP gene. May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). Essential for maintaining a vascular smooth muscle cells (VSMCs) contractile/differentiated phenotype under physiological and pathological stimuli. Maintains this phenotype of VSMCs by interacting with ITGA7 (By similarity).

COMP Antibodies

COMP Antibodies for Homo sapiens (Human)

COMP Proteins

COMP Proteins for Rattus norvegicus (Rat)

COMP Proteins for Bos taurus (Bovine)

COMP Proteins for Homo sapiens (Human)

COMP Proteins for Mus musculus (Mouse)

COMP Proteins for Bacillus subtilis (strain 168)


COMP ELISA Kit for Homo sapiens (Human)

COMP ELISA Kit for Mus musculus (Mouse)

COMP ELISA Kit for Rattus norvegicus (Rat)


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