HCRTR1, the hypothalamic neuropeptide orexin receptor 1, modulates physiological functions such as food intake, sleep-wake cycles, and stress response. It activates the G protein-coupled signal transduction pathway upon binding to orexin A, influencing intracellular signaling cascades. HCRTR1 is crucial for sleep regulation, energy metabolism, and stress response, with its dysfunction associated with insomnia, narcolepsy, and obesity, making it a potential drug development target.
Recombinant Human Orexin receptor type 1 (HCRTR1) (CSB-YP010231HU1)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
HCRTR1 Antibody (CSB-PA797469)
Validated Data
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA797469(HCRTR1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA797469(HCRTR1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
The following HCRTR1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
HCRTR1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA010231GA01HU | HCRTR1 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA009162 | HCRTR1 Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA009167 | HCRTR1 Antibody | Human,Mouse,Rat | IF, ELISA |
CSB-PA797469 | HCRTR1 Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA153820 | HCRTR1 Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA010231HA01HU | HCRTR1 Antibody | Human | ELISA, IF |
CSB-PA010231HB01HU | HCRTR1 Antibody, HRP conjugated | Human | ELISA |
CSB-PA010231HC01HU | HCRTR1 Antibody, FITC conjugated | Human | |
CSB-PA010231HD01HU | HCRTR1 Antibody, Biotin conjugated | Human | ELISA |
HCRTR1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF010231MO | Recombinant Mouse Orexin/Hypocretin receptor type 1 (Hcrtr1) | in vitro E.coli expression system |
CSB-YP010231MO1 CSB-EP010231MO1 CSB-BP010231MO1 CSB-MP010231MO1 CSB-EP010231MO1-B |
Recombinant Mouse Orexin/Hypocretin receptor type 1 (Hcrtr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HCRTR1 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-CF010231RA | Recombinant Rat Orexin receptor type 1 (Hcrtr1) | in vitro E.coli expression system |
CSB-YP010231RA1 CSB-EP010231RA1 CSB-BP010231RA1 CSB-MP010231RA1 CSB-EP010231RA1-B |
Recombinant Rat Orexin receptor type 1 (Hcrtr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HCRTR1 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-CF606357BO | Recombinant Bovine Orexin receptor type 1 (HCRTR1) | in vitro E.coli expression system |
CSB-YP606357BO1 CSB-EP606357BO1 CSB-BP606357BO1 CSB-MP606357BO1 CSB-EP606357BO1-B |
Recombinant Bovine Orexin receptor type 1 (HCRTR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HCRTR1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF010231HU | Recombinant Human Orexin receptor type 1 (HCRTR1) | in vitro E.coli expression system |
CSB-EP010231HU1 | Recombinant Human Orexin receptor type 1 (HCRTR1), partial | E.coli |
CSB-BP010231HU1 CSB-MP010231HU1 CSB-EP010231HU1-B |
Recombinant Human Orexin receptor type 1 (HCRTR1), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-YP010231HU1 | Recombinant Human Orexin receptor type 1 (HCRTR1) | Yeast |
HCRTR1 Proteins for Sus scrofa (Pig)
Code | Product Name | Source |
---|---|---|
CSB-YP010231PI CSB-EP010231PI CSB-BP010231PI CSB-MP010231PI CSB-EP010231PI-B |
Recombinant Pig Orexin receptor type 1 (HCRTR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |