LCN2 Research Reagents

Neutrophil gelatinase-associated lipocalin is a protein in humans that is encoded by LCN2 gene. Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation

The following LCN2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

LCN2 Antibodies

LCN2 Antibodies for Homo sapiens (Human)

LCN2 Antibodies for Mus musculus (Mouse)

LCN2 Antibodies for Rattus norvegicus (Rat)

LCN2 Proteins

LCN2 Proteins for Mus musculus (Mouse)

LCN2 Proteins for Rattus norvegicus (Rat)

LCN2 Proteins for Homo sapiens (Human)


LCN2 ELISA Kit for Mus musculus (Mouse)

LCN2 ELISA Kit for Rattus norvegicus (Rat)

LCN2 ELISA Kit for Homo sapiens (Human)

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