MRAS (Muscle RAS Oncogene Homolog) plays a significant role in cellular signal transduction pathways. It belongs to the small GTPase family and regulates various cell signaling pathways by modulating its binding state with GTP and GDP at the cell membrane. MRAS can regulate processes such as cell growth, differentiation, and survival by either activating or inhibiting downstream signaling molecules. MRAS is widely expressed in various cell types, including muscle cells and cells from numerous other tissues. While some aspects of MRAS's function and regulatory mechanisms resemble those of other RAS family members, it also possesses distinct functions and regulatory modalities of its own. Its involvement in cellular signal transduction and its associations with the onset and progression of diseases underscore its crucial significance.
● MRAS Recombinant Monoclonal Antibody CSB-RA014781MA1HU
Validated Data
IHC image of CSB-RA014781MA1HU diluted at 1:600 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Mouse IgG labeled by HRP and visualized using 0.05% DAB.
Immunofluorescence staining of Hela cell with CSB-RA014781MA1HU at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Mouse IgG(H+L).
The following MRAS reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
MRAS Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA014781GA01HU | MRAS Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA014781ESR1HU | MRAS Antibody | Human, Mouse | ELISA, WB |
CSB-PA014781ESR2HU | MRAS Antibody | Human, Mouse | ELISA, WB, IHC |
CSB-PA014781LA01HU | MRAS Antibody | Human | ELISA, IF |
CSB-PA014781LD01HU | MRAS Antibody, Biotin conjugated | Human | ELISA |
CSB-PA014781LC01HU | MRAS Antibody, FITC conjugated | Human | |
CSB-RA158563A0HU | MRAS Recombinant Monoclonal Antibody | Human | ELISA, WB |
CSB-RA014781MA1HU | MRAS Recombinant Monoclonal Antibody | Human | ELISA, IHC, IF |
MRAS Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP014781RA CSB-EP014781RA CSB-BP014781RA CSB-MP014781RA CSB-EP014781RA-B |
Recombinant Rat Ras-related protein M-Ras (Mras) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MRAS Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP014781MO CSB-EP014781MO CSB-BP014781MO CSB-MP014781MO CSB-EP014781MO-B |
Recombinant Mouse Ras-related protein M-Ras (Mras) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MRAS Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP014781HU CSB-BP014781HU CSB-MP014781HU CSB-EP014781HU-B |
Recombinant Human Ras-related protein M-Ras (MRAS) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP014781HU | Recombinant Human Ras-related protein M-Ras (MRAS) | E.coli |