Neurogenic locus notch homolog protein 3 is a protein in humans that is encoded by NOTCH3 gene. Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity).
The following NOTCH3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
NOTCH3 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA015952GA01HU | NOTCH3 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA586591 | NOTCH3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA892153LA01HU | NOTCH3 Antibody | Human | ELISA, IHC |
CSB-PA892153LB01HU | NOTCH3 Antibody, HRP conjugated | Human | ELISA |
CSB-PA892153LC01HU | NOTCH3 Antibody, FITC conjugated | Human | |
CSB-PA892153LD01HU | NOTCH3 Antibody, Biotin conjugated | Human | ELISA |
NOTCH3 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP733800MO CSB-EP733800MO CSB-BP733800MO CSB-MP733800MO CSB-EP733800MO-B |
Recombinant Mouse Neurogenic locus notch homolog protein 3 (Notch3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOTCH3 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP865638RA CSB-EP865638RA CSB-BP865638RA CSB-MP865638RA CSB-EP865638RA-B |
Recombinant Rat Neurogenic locus notch homolog protein 3 (Notch3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOTCH3 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP892153HU CSB-EP892153HU CSB-BP892153HU CSB-MP892153HU CSB-EP892153HU-B |
Recombinant Human Neurogenic locus notch homolog protein 3 (NOTCH3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOTCH3 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL015952HU | Human Neurogenic locus notch homolog protein 3(NOTCH3) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 31.25 pg/mL |