cAMP-dependent protein kinase catalytic subunit alpha is a protein in humans that is encoded by PRKACA gene. Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose-mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts.
The following PRKACA reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PRKACA Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA018688GA01HU | PRKACA Antibody | Human | ELISA,WB |
CSB-PA157769 | Phospho-PRKACA (Thr197) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA235804 | PRKACA Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA030210 | Phospho-PRKACA (S338) Antibody | Human,Mouse,Rat | IHC, ELISA |
CSB-PA018688LA01HU | PRKACA Antibody | Human | ELISA, WB, IHC |
CSB-PA018688LB01HU | PRKACA Antibody, HRP conjugated | Human | ELISA |
CSB-PA018688LC01HU | PRKACA Antibody, FITC conjugated | Human | |
CSB-PA018688LD01HU | PRKACA Antibody, Biotin conjugated | Human | ELISA |
PRKACA Antibodies for Canis lupus familiaris (Dog) (Canis familiaris)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA822648ZA01FQF | PRKACA Antibody | Canis lupus familiaris | ELISA, WB (ensure identification of antigen) |
PRKACA Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP018688HU CSB-BP018688HU CSB-MP018688HU CSB-EP018688HU-B |
Recombinant Human cAMP-dependent protein kinase catalytic subunit alpha (PRKACA) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP018688HU | Recombinant Human cAMP-dependent protein kinase catalytic subunit alpha (PRKACA) | E.coli |
PRKACA Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP018688RA CSB-EP018688RA CSB-BP018688RA CSB-MP018688RA CSB-EP018688RA-B |
Recombinant Rat cAMP-dependent protein kinase catalytic subunit alpha (Prkaca) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKACA Proteins for Sus scrofa (Pig)
Code | Product Name | Source |
---|---|---|
CSB-YP018688PI CSB-EP018688PI CSB-BP018688PI CSB-MP018688PI CSB-EP018688PI-B |
Recombinant Pig cAMP-dependent protein kinase catalytic subunit alpha (PRKACA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKACA Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP018688MO CSB-EP018688MO CSB-BP018688MO CSB-MP018688MO CSB-EP018688MO-B |
Recombinant Mouse cAMP-dependent protein kinase catalytic subunit alpha (Prkaca) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKACA Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP018688BO CSB-EP018688BO CSB-BP018688BO CSB-MP018688BO CSB-EP018688BO-B |
Recombinant Bovine cAMP-dependent protein kinase catalytic subunit alpha (PRKACA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKACA Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Code | Product Name | Source |
---|---|---|
CSB-YP018688DXU CSB-EP018688DXU CSB-BP018688DXU CSB-MP018688DXU CSB-EP018688DXU-B |
Recombinant Cricetulus griseus cAMP-dependent protein kinase catalytic subunit alpha (PRKACA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKACA Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
Code | Product Name | Source |
---|---|---|
CSB-YP822648DO CSB-BP822648DO CSB-MP822648DO CSB-EP822648DO-B |
Recombinant Dog cAMP-dependent protein kinase catalytic subunit alpha (PRKACA) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP822648DO | Recombinant Dog cAMP-dependent protein kinase catalytic subunit alpha (PRKACA) | E.coli |
PRKACA Proteins for Ovis aries (Sheep)
Code | Product Name | Source |
---|---|---|
CSB-YP865034SH CSB-EP865034SH CSB-BP865034SH CSB-MP865034SH CSB-EP865034SH-B |
Recombinant Sheep cAMP-dependent protein kinase catalytic subunit alpha (PRKACA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |