PRKACA

cAMP-dependent protein kinase catalytic subunit alpha is a protein in humans that is encoded by PRKACA gene. Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose-mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts.

PRKACA Antibodies

PRKACA Antibodies for Homo sapiens (Human)

PRKACA Proteins

PRKACA Proteins for Homo sapiens (Human)

PRKACA Proteins for Rattus norvegicus (Rat)

PRKACA Proteins for Sus scrofa (Pig)

PRKACA Proteins for Mus musculus (Mouse)

PRKACA Proteins for Bos taurus (Bovine)

PRKACA Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

PRKACA Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

PRKACA Proteins for Ovis aries (Sheep)

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