Ribosomal protein S6 kinase beta-1 is a protein in humans that is encoded by RPS6KB1 gene. Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex. Upon mitogenic stimulation, phosphorylation by the mammalian target of rapamycin complex 1 (mTORC1) leads to dissociation from the EIF3 complex and activation. The active form then phosphorylates and activates several substrates in the pre-initiation complex, including the EIF2B complex and the cap-binding complex component EIF4B.

RPS6KB1 Antibodies

RPS6KB1 Antibodies for Homo sapiens (Human)

RPS6KB1 Antibodies for Human

RPS6KB1 Proteins

RPS6KB1 Proteins for Oryctolagus cuniculus (Rabbit)

RPS6KB1 Proteins for Homo sapiens (Human)

RPS6KB1 Proteins for Rattus norvegicus (Rat)

RPS6KB1 Proteins for Bos taurus (Bovine)

RPS6KB1 Proteins for Mus musculus (Mouse)


RPS6KB1 ELISA Kit for Homo sapiens (Human)


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