RUNX1

Runt-related transcription factor 1 is a protein in humans that is encoded by RUNX1 gene. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits KAT6B-dependent transcriptional activation. Controls the anergy and suppressive function of regulatory T-cells (Treg) by associating with FOXP3.

RUNX1 Antibodies

RUNX1 Antibodies for Homo sapiens (Human)

RUNX1 Antibodies for Human

RUNX1 Proteins

RUNX1 Proteins for Rattus norvegicus (Rat)

RUNX1 Proteins for Xenopus laevis (African clawed frog)

RUNX1 cDNA for Rattus norvegicus (Rat)

Code Product Name Vector Accession NO.
CSB-CL020592RA Runx1 pUC NM_017325.1

RUNX1 ELISA Kit

RUNX1 ELISA Kit for Rattus norvegicus (Rat)

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