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E3 ubiquitin-protein ligase SMURF1 is a protein in humans that is encoded by SMURF1 gene. E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Promotes ubiquitination and subsequent proteasomal degradation of MAVS.
The following Smurf1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
Smurf1 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA021860GA01HU | SMURF1 Antibody |
Human,Mouse,Rat | ELISA,WB |
| CSB-PA026284 | SMURF1 Antibody |
Human,Mouse | ELISA,IHC |
| CSB-PA875720LA01HU | SMURF1 Antibody |
Human | ELISA, WB, IF |
| CSB-PA875720LB01HU | SMURF1 Antibody, HRP conjugated |
Human | ELISA |
| CSB-PA875720LC01HU | SMURF1 Antibody, FITC conjugated |
Human | |
| CSB-PA875720LD01HU | SMURF1 Antibody, Biotin conjugated |
Human | ELISA |
| CSB-MA875720A0m | SMURF1 Monoclonal Antibody |
Human | ELISA, WB, IHC, IF, FC |
Smurf1 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP875137MO CSB-EP875137MO CSB-BP875137MO CSB-MP875137MO CSB-EP875137MO-B |
Recombinant Mouse E3 ubiquitin-protein ligase SMURF1 (Smurf1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Smurf1 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP875720HU CSB-EP875720HU CSB-BP875720HU CSB-MP875720HU CSB-EP875720HU-B |
Recombinant Human E3 ubiquitin-protein ligase SMURF1 (SMURF1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Smurf1 Proteins for Xenopus laevis (African clawed frog)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP886105XBE CSB-EP886105XBE CSB-BP886105XBE CSB-MP886105XBE CSB-EP886105XBE-B |
Recombinant Xenopus laevis E3 ubiquitin-protein ligase SMURF1 (smurf1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Smurf1 ELISA Kit for Mus musculus (Mouse)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL021860MO | Mouse E3 ubiquitin-protein ligase SMURF1(SMURF1) ELISA kit |
serum, plasma, tissue homogenates, cell lysates | 7.8 pg/mL |
