Code | CSB-E04631h |
Size | 96T,5×96T,10×96T |
Trial Size | ![]() |
Have Questions? | Leave a Message or Start an on-line Chat |
Description |
This human IL-3 ELISA kit employs the quantitative sandwich enzyme immunoassay technique to measure the levels of human IL-3 in multiple samples, including serum, plasma, or tissue homogenates. It also uses the enzyme-substrate chromogenic reaction to visualize and analyze the analyte levels through the color intensity. The intensity of the colored product is in direct proportion to the IL-3 levels in the sample and is measured at 450 nm through a microplate reader. IL-3 is primarily produced by activated T-cells and plays a critical role in the activation and survival of a diverse group of cells, including mast cells and basophils, monocytes, B cells, T cells, and endothelial cells. IL-3 is involved in the hematopoietic response to infectious, immunologic, and inflammatory stimuli. Studies have shown that IL-3 contributes to inflammation and autoimmunity. IL-3 acts by binding to high-affinity cell surface receptors present on hematopoietic cells. IL-3/IL-3Rα signaling is responsible for cytokine storms during the pathogenesis of cecal ligation and puncture-induced sepsis and is suggested as a potential therapeutic target for sepsis. |
Alternative Names | Colony stimulating factor multiple ELISA Kit; Hematopoietic growth factor ELISA Kit; IL 3 ELISA Kit; IL-3 ELISA Kit; IL3 ELISA Kit; IL3_HUMAN ELISA Kit; Interleukin 3 (colony stimulating factor; multiple) ELISA Kit; Interleukin 3 ELISA Kit; Interleukin-3 ELISA Kit; Mast cell growth factor ELISA Kit; MCGF ELISA Kit; MGC79398 ELISA Kit; MGC79399 ELISA Kit; Multi CSF ELISA Kit; Multilineage colony stimulating factor ELISA Kit; Multipotential colony stimulating factor ELISA Kit; Multipotential colony-stimulating factor ELISA Kit; OTTHUMP00000065963 ELISA Kit; P cell stimulating factor ELISA Kit; P-cell-stimulating factor ELISA Kit |
Abbreviation | IL3 |
Uniprot No. | P08700 |
Species | Homo sapiens (Human) |
Sample Types | serum, plasma, tissue homogenates. |
Detection Range | 62.5 pg/ml-4000 pg/ml. |
Sensitivity | 15.6 pg/ml. |
Assay Time | 1-5h |
Sample Volume | 50-100ul |
Detection Wavelength | 450 nm |
Research Area | Immunology |
Assay Principle | quantitative |
Measurement | Sandwich |
ELISA Data Analysis | Watch ELISA data processing video & download Curve Expert if needed |
Troubleshooting and FAQs |
ELISA kit FAQs |
Storage | Store at 2-8°C. Please refer to protocol. |
Lead Time | 3-5 working days |
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Function (From Uniprot) |
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.; This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
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Gene References into Functions |
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Subcellular Location | Secreted. |
Protein Families | IL-3 family |
Tissue Specificity | Activated T-cells, mast cells, natural killer cells. |
Database Links |
HGNC: 6011 OMIM: 147740 KEGG: hsa:3562 STRING: 9606.ENSP00000296870 UniGene: Hs.694 |